Derek Lowe

  • Dusty reagent bottles
    Opinion

    Death of a reagent

    22 August 2014

    Fashion and progress combine to mean some reactions and reagents persist, while others fall by the wayside, says Derek Lowe

  • Molecular structure in crystal ball
    Opinion

    The crystal ball that can tell lies

    29 July 2014

    X-ray structures are not necessarily definitive, says Derek Lowe, especially when it comes to biomolecules

  • CW0714_Pipeline_630m
    Opinion

    Too big to innovate?

    25 June 2014

    How strong is the correlation between company size and research productivity, asks Derek Lowe

  • 0614CW_PIPELINE_300m
    Opinion

    Messy megamergers

    29 May 2014

    Big company buyouts are more about immediate gains and rarely consider the impact on research, says Derek Lowe

  • PIPELINE_300M
    Opinion

    Engineering serendipity

    25 April 2014

    It takes more than random stumbling to find new reactions, says Derek Lowe

  • Man in respirator with smoking flask
    Opinion

    Known unknowns

    27 March 2014

    New molecules with unpredictable biological activity deserve sensible amounts of respect, says Derek Lowe

  • Mystery box concept image
    Opinion

    Tools of the trade

    24 February 2014

    Derek Lowe wonders what the most life-changing instrument for organic chemists is, and what might be missing from the toolbox

  • devilish manager at computer
    Opinion

    Beelzebub Pharma Ltd

    31 January 2014

    Derek Lowe thinks the Devil’s R&D management schemes might be scarily familiar

  • Hammer and nails
    Opinion

    Is there a drug for that?

    7 January 2014

    Derek Lowe ponders whether anything is truly ‘undruggable’ if we look in the right places

  • cartoon of workers pushing a boulder up a hill with a manager on the boulder
    Opinion

    Rolling boulders uphill

    27 November 2013

    Is Derek Lowe troubled by his failure to develop a compound that has made it to the pharmacy shelf?