Derek Lowe

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    Too big to innovate?

    25 June 2014

    How strong is the correlation between company size and research productivity, asks Derek Lowe

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    Messy megamergers

    29 May 2014

    Big company buyouts are more about immediate gains and rarely consider the impact on research, says Derek Lowe


    Engineering serendipity

    25 April 2014

    It takes more than random stumbling to find new reactions, says Derek Lowe

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    Known unknowns

    27 March 2014

    New molecules with unpredictable biological activity deserve sensible amounts of respect, says Derek Lowe

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    Tools of the trade

    24 February 2014

    Derek Lowe wonders what the most life-changing instrument for organic chemists is, and what might be missing from the toolbox

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    Beelzebub Pharma Ltd

    31 January 2014

    Derek Lowe thinks the Devil’s R&D management schemes might be scarily familiar

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    Is there a drug for that?

    7 January 2014

    Derek Lowe ponders whether anything is truly ‘undruggable’ if we look in the right places

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    Rolling boulders uphill

    27 November 2013

    Is Derek Lowe troubled by his failure to develop a compound that has made it to the pharmacy shelf?

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    Natural born chemists

    31 October 2013

    Redesigning nature’s catalysts is tantalising but tricky, says Derek Lowe

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    What's the use?

    25 September 2013

    Not every reaction can be run in a bucket, says Derek Lowe, but there are limits to what should be classed as ‘useful’