All Clinical Trials articles – Page 3
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FeatureThe long road to an HIV vaccine
A vaccine may not be available anytime soon, but its proponents are hard at work
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Business
AstraZeneca shares tumble after antibody failure
Imfinzi and tremelimumab checkpoint inhibitor pairing fails to beat chemotherapy in lung cancer
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Research
Lilly pushes continuous drug production limits
Integrated flow synthesis and purification process for prexasertib meets high industry standards
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Opinion
Unpicking a clinical trial death
A new study shows up off-target effects of a drug that proved deadly, and highlights the pitfalls of drug discovery
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Opinion
How safe should drugs be?
What does spotting new risks in approved medicines say about how effective regulators are?
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Research
Catalyst puts chiral twist on phosphorus drugs
Simple molecule overcomes headache of phosphorus stereochemistry in antiviral drug synthesis
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News
Fears that gene-editing cancer trials are premature
Warnings from geneticists that Crispr trial failures could knock promising technique’s prospects
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Opinion
Regulatory tightropes
When lobbying and marketing clash with scientific evidence, regulators walk a fine line
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Business
FDA urges labs to test all blood donations for Zika
Agency has also given emergency authorisation to two new Zika blood tests
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Business
Juno CAR-T trial suspended after patient deaths
Immunotherapy study restarted with amended pre-treatment protocol
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News
Large HIV vaccine trial to launch in South Africa
US funding agency will enlist 5400 people for HIV vaccine study in South Africa in November
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News
Insider trading scandal topples head of Taiwan’s top research body
President of umbrella organisation overseeing 24 research institutions caught up in investigation into offloading of biotech shares prior to poor results
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Business
Clinical trial death highlights hazards
Pain drug trial has left one dead and five hospitalised in France, with little indication as to the cause of the problems
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Business
EU regulator calls for generic drug suspensions
The EMA wants hundreds of formulations off the market after identifying systematic fraud in a major Indian contract clinical research organisation
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News
Tufts’ $2.6bn drug development figure questioned
Details sought about how university determined cost of bringing a drug to market jumped 145% since 2003
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News
Ebola vaccine passes first safety hurdle
Researchers hope to begin larger trials of its effectiveness in west Africa soon
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News
US agency fast-tracks Ebola vaccine development
Health and Human Services invests almost $6 million to ready an Ebola vaccine candidate for clinical trials, meanwhile GSK says its vaccine is progressing at an ‘unprecedented rate’
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Business
EMA finalises trial transparency rules
Researcher access reinstated, but company redaction rights may cause issues
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Feature
Transparency measures forced on pharma
Previous misdemeanours are compelling the pharmaceutical industry to be more open with financial information and clinical data, writes Nuala Moran
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News
NIH wants scientists to consider sex in research
Preclinical and clinical research is overreliant on male test subjects which can cloud future work in humans
