Derek Lowe – Page 9
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Opinion
If something can’t go on, then it won’t
Derek Lowe looks into his crystal ball to see what the future of medicinal chemistry might be
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OpinionDeath by assay result
Derek Lowe wonders whether tagging molecules with fluorescent labels for assay is like tracking the members of a shoal of fish by tying each one to a whale
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Opinion
How to be an organised scientist
Derek Lowe waxes lyrical about the joys of the electronic lab notebook
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Opinion
Papers vs patents
Derek Lowe wonders whether peer-reviewed papers or patents are more reliable
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Opinion
The sincerest form of flattery
Is the pharmaceutical industry churning out copycat versions of existing therapies? Derek Lowe dispels a few myths about 'me-too' drugs
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Opinion
Senseless screening
Derek Lowe advises opening your mind during the screening cascade taken by potential drug targets, and remaining goal orientated at all times
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Opinion
Reliable reactions
Derek Lowe discusses the problem of leaning too heavily on favourite reactions
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Opinion
Difficult diseases to drug
Derek Lowe wonders why some diseases are easier to drug than others
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Opinion
Beautiful chemistry
Derek Lowe considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder
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Opinion
Formulation chemist friction
Derek Lowe wonders where we'd be without the formulation chemists
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Opinion
Collaborative compromise
Derek Lowe wonders about pharmaceutical companies' motives for collaboration
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Opinion
Prescription unknowns
Derek Lowe considers what we think we know about how drugs work once we've taken them
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Opinion
Stick to the steps
Derek Lowe considers the problems of addressing drug development out of sequence
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Opinion
A new wave of consolidation
Derek Lowe worries that mergers are upsetting the balance of the pharmaceutical ecosystem
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Opinion
Cutting-edge technology for cutting-edge results?
How important is it to have the best equipped lab, wonders Derek Lowe