Medicine and health – Page 8
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Research
Water pipe technology kills microorganisms with localised electric field
Flowing water could power smart pipes
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Research
Chemists complete synthesis of molecule ‘at the limits of complexity’
Synthesis of canataxpropellane paves the way to biological studies
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Research
First Crispr cancer trial in humans shows safety and durability
Immune-cell modifications target tumours and lift the PD-1 ‘brake’
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Test for antibiotic resistance genes provides answers within an hour
Whole blood method for diagnosing bacterial infections has unprecedented speed and sensitivity
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Warning that 3D printing pills can stop drugs working
Photoreactive monomers need close scrutiny for production of polypills
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Research
Sugars designed to disrupt bacterial cell wall biosynthesis
Rare monosaccharides explore concept for new narrow-spectrum antibiotics
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Research
Brake dust damages lungs as much as diesel exhaust fumes
Landmark study highlights a new avenue for air pollution research
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Research
Synthetic strategy exploits fluxional nitrogen to deliver three chiral centres for the price of one
Innovative method amplifies chirality and complexity in medicinally relevant cyclic hydrazines
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Research
E-liquids linked to US deaths form deadly compound when vaped
Pyrolysis of vitamin E acetate creates organic molecule with effects comparable to first world war chemical weapon
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Research
Compact pharmaceutical factory manufactures drugs on demand
Plant with modular design would occupy about half the area of a squash court
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Inorganic fragment library ready to help drug discoverers reach neglected regions of chemical space
A new approach to fragment-based drug design
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Research
Total synthesis of H. pylori antigen creates starting point for gastric cancer vaccine
Remote participation strategy helps chemists make sterically-congested repeating fragment
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Research
Smart contact lens can be charged up wirelessly while it’s worn
LED, antenna and printable supercapacitor built into lens without obscuring wearer’s vision
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Research
Spectroscopic biomarkers track Huntington’s disease progression
Analysis recognises biochemical changes that are unique to Huntington’s
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Engineered insulin with enhanced thermal stability inspired by fish-hunting snails
Four-disulfide insulin has similar bioactivity to native human insulin
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Flow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
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Research
Ammonium bicarbonate trick enables sophisticated lipid analysis
Tandem mass spectrometry method can distinguish lipid isomers
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Research
Alzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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Research
Metallohelices emulate antimicrobial peptides
Scientists move away from traditional drug candidates to evade resistance
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Research
Elusive protein and key to many tropical diseases found after decades of searching
Discovery offers powerful new target to treat trypanosome parasite illnesses that affect millions