Organic matter – Page 4
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OpinionMaking light work of synthesis
The LED zeppelin is flying high, but is it all hot air asks Karl Collins
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OpinionA sideways look at synthesis
Side products might not be what you want, but they could be what you need
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OpinionKetones perform at the palladium
C–H activation takes the stress out of organometallic couplings
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OpinionChanging the reproducibility rulebook
It pays to know when taking shortcuts is acceptable, and which it’s safe to take
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OpinionBeyond buckets and batches
Embracing flow chemistry means leaving behind some faithful friends
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Opinion(‒)-Pavidolide B
An innovative approach to making five-membered carbon rings makes for a strikingly short synthesis
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OpinionForcing fluorines into shape
Sometimes unnatural molecules can be more challenging to synthesise than natural metabolites
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Opinion(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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OpinionNickel catalyst couples alcohols and carbon dioxide
Flexibility and low cost make nickel a firm favourite in catalysis
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OpinionCrystal clear
The dark craft of crystallisation is an essential skill when working on kilogram scale
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Opinion(+)-Zincophorin methyl ester
New and old reactions combine for an elegant and concise synthesis
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OpinionIn search of solvation
Process chemistry opens up a whole new world when it comes to solvent choice
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OpinionFunctionalising pyridines with phosphonium salts
Newly-independent research groups often bring new perspectives to synthesis