By Ben Valsler
How did a tree bark from Sri Lanka become one of the essential flavours of the festive season?
A compound so explosively unstable that nobody has been able to measure how sensitive it is without it, well, exploding
How one of mankind’s oldest pigments helped shepherds secure their sheep and inspired one of the most popular songs of the twentieth century
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A sweet compound that provides ample energy for extreme endurance events
Liquid salts, ionic melts, fused salts, or ionic glasses – call them what you like, these much-hyped solvents show great promise
An antimicrobial compound that kills bacteria and viruses quickly – found in some of the most colourful antiseptic solutions
By Helen Arney
Does asparagus give you foul-smelling urine? Helen Arney investigates asparagusic acid, and the lavatorial genetic lottery that controls whether or not you can smell its distinctive aroma
By Ben Valsler
A sweet treat with a deadly trick for Halloween – glycyrrhizic acid is found in black liquorice and sweeter than sucrose, but can cause heart problems and even prove fatal if consumed in excess
Also known as ‘milk of amnesia’, propofol helps to prevent perception of pain in surgery – just don’t forget its dangerous side
The hepatitis C drug that made waves when first launched – quicker to work and with fewer side effects than existing drugs, but it came with a hefty price tag
The first TB drug approved in 40 years gave hope to sufferers of drug resistant tuberculosis and ushered in a new class of antibiotics
This summer’s extreme weather prompts Katrina Krämer to investigate the history of sunblock and the ingredient blamed by some for bleaching coral reefs
From Lavoisier’s experiments with plaster of paris to the the ‘Sistine Chapel of crystals’ in Mexico, Mike Freemantle explores the history of gypsum
By Ben Valsler
Originally developed to treat flu and marketed in Japan as Avigan, promising Covid-19 trial results have seen countries stockpiling this medication by the millions
Tannic acid in green acorns can kill wild animals and livestock, but you can prevent poisoning with pannage pigs
By Ben Valsler
Common in the US but banned in the EU, this animal feed additive makes for muscular pigs and beefy international trade disputes.
By Brian Clegg
Brian Clegg discovers what a six-membered silicon ring can tell us about alien life
Frances Addison on the aromatic compound found in both buttered popcorn and the bearcat’s scent glands, and responsible for the distinctive smell of both
By Ben Valsler
News that this cheap, ubiquitous steroid drug may reduce deaths in Covid-19 cases has been greeted with cautious optimism
Mike Freemantle on the art, history and science of this delicate, translucent ceramic material
By Brian Clegg
Brian Clegg introduces the humble mineral that delights both astronomers and archaeologists
Mike Freemantle introduces the peptic ulcer treatment cimetidine, which – as Tagamet – became the first blockbuster drug
The World Health Organisation hope to eradicate sleeping sickness within our lifetimes. Jamie Durrani looks at a drug that may make it possible.
Georgia Mills investigates the psychoactive found in ayahuasca that may mirror near-death experiences
Katrina Krämer investigates how industrial-strength bleach became promoted as ‘miracle mineral supplement’ – a supposed ‘cure’ for autism, cancer and even Covid-19.
By Brian Clegg
Brian Clegg discovers the link between olive oil, dandruff and stained glass windows.
By Ben Valsler
An immune-modulating compound used to reduce the symptoms of multiple sclerosis and now showing potential against coronaviruses
The unexplained appearance and dramatic spread of a new form of HIV drug ritonavir hurt patients and cost its makers almost $250 million.
By Ben Valsler
How a drug that prevents HIV from donning its protective ‘coat’ now makes up one arm of the World Health Organisation’s Covid-19 trial
By Ben Valsler
Will new clinical trials for Covid-19 give remdesivir a second chance? Ben Valsler introduces the broad-spectrum antiviral that didn’t quite make it as the Ebola drug it was originally planned to be
By Ben Valsler
The Covid-19 pandemic – and some very high profile backing – has led to malaria drugs chloroquine and hydroxychloroquine hitting the headlines worldwide.
By Brian Clegg
Brian Clegg on the popular over-the-counter painkiller, developed by a high-street pharmacy chain
Catherine Hodges explores the chemical solutions to thinning hair and patchy beards, examining the popularity of minoxidil and the cautionary tale of finasteride
The pesticide that keeps pets free of pests, but may have also been responsible for the devastating collapse of bee colonies
Rotund rodents revolutionised our understanding of the biological role of fat. Now, as Katrina Krämer discovers, the hormones created by fats could redefine obesity
By Ben Valsler
Ben Valsler on vitamin K – the blood clotting factor that is likely to be the first supplement you ever receive
By Brian Clegg
Brian Clegg on the enzymes make life a little sweeter by breaking down starch into sugars, helping to make bread and beer
Georgia Mills on a compound that explodes from a beetle’s bum, and has a controversial role in skin depigmentation
This week marks the 20th anniversary of the Baia Mare disaster, when toxic sodium cyanide spilled from a gold processing plant led to ecological damage on a huge scale.
By Brian Clegg
Once thought of as an interesting – but useless – turpentine derivative, this oddly-named acid became the precursor to one of the world’s most widely used plastics
From ancient Egyptian pottery to distinctive blue bottles, cobalt oxide has been providing ‘chemically and artistically perfect’ pigments for centuries
By Ben Valsler
If you’re trying out a vegan diet, you’re likely to be told to make sure you get enough vitamin B12. But what is B12, where do we get it from, and how can we be sure we’re getting enough?
To see out the International Year of the Periodic Table in style, we’ve brought Tom Lehrer’s classic periodic table patter up to date
After some promising results treating ill pets, some researchers think iminosugars could become treatments for infection and even cancer. Mike Freemantle explores the buzz around iminohoney
Frances Addison examines how our quest to control and manage pain has led to a modern medical crisis, as opioids oxycodone and hydrocodone are among the most abused prescription medications in the US
By Ben Valsler
Ben Valsler tackles ‘zombie facts’ and the tenuous connection between tryptophan in turkey and your post-Thanksgiving dinner doze
By Brian Clegg
Brian Clegg introduces the class of materials where the holes are more important than the whole – the super-porous zeolites
It helps prevent garlic plants from marauding insects and should have prevented the Hindenburg disaster – Mike Freemantle on allicin and the smell of freshly crushed garlic
By Louise Crane
Louise Crane explains how a series of happy accidents led to the discovery of this rose-scented compound, found in rose oil, beer, apple pie and Kentucky bourbon.
By Brian Clegg
Brian Clegg introduces gallium arsenide – the supercar of the semiconductor scene
Georgia Mills introduces the malleable mixture of gold and silver that minted some of the world’s oldest coins
By Ben Valsler
The oxygen sensors that help life react to changing conditions, key to the 2019 Nobel prize in physiology or medicine
The toxin found in reef fish that leads to food poisoning so bad it can cause life-long symptoms
How a Brazilian scientist’s knowledge of viper venom led to the discovery of a whole class of medication for high blood pressure. With Mike Freemantle
By Louise Crane
Louise Crane investigates a jasmine-derived synthetic scent with supposed sex appeal
The controversial killer compound – also known as 1080 – being used to protect New Zealand’s native wildlife
The marine toxin that drives animals crazy and might have inspired one of Alfred Hitchcock’s most famous films
Mike Freemantle revisits battlefield surgery to investigate boric acid, a key part of Dakin's antiseptic solution used extensively in the first world war
Patrick Hughes delves into the molecule at the centre of a decades-old cancer treatment conspiracy theory
Georgia Mills tackles the feel-good neurotransmitter and hormone behind thrill seeking, addiction, and mobile gaming
Mike Freemantle finds the connection between Land of Hope and Glory and the noxious, corrosive, flammable gas that stinks of rotten eggs
One doctor's battle with alcoholism and self-experimentation with baclofen led to a rush of people desperate to try the drug to curb their addictions. But are we simply replacing one problem with another, asks Enna Guadalupe
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