Long reads
Breaking the silence of RNA interference drugs
A wave of treatments is set to follow the first approval of an RNAi therapy
Cleaning up clinical trials
Campaigns to enforce complete and correct reporting of trial data are beginning to take hold
Building resilience to climate threats
As extreme weather events become more frequent, chemical and pharmaceutical producers are taking steps to fend them off in future
Profiles
Sensing the sweet spot
Ziylo’s selective glucose-binding molecule could open doors to smart insulin for diabetes
Transforming PET imaging with silicon
Fuzionaire Diagnostics can add Si–18F radiolabels to a variety of molecules quickly, easily and cheaply
Rural power champion
Clementine Chambon is the 2018 Chemistry World Entrepreneur of the Year for her work using bioenergy to solve environmental, social and gender challenges in rural India
From chemist to patent attorney
How to make the career switch
Opinion
Pushing the limits of patent protection
Some methods of extending exclusivity rights raise legal and ethical questions
How do you keep plant reactions cold?
When a really big tub of ice just doesn’t cut it
What would a 1980s student make of modern research?
Nano- and macromolecular science might make for a shocking read in the launderette
Passing through checkpoints
A new breed of cancer treatments highlights what’s possible when industry concentrates its efforts
More Business News
Cancer immunotherapy spreads rapidly
New approvals and expanded use for checkpoint inhibitor drugs illustrate the power of Nobel-winning science
Novartis to cut over 2000 jobs
Move exemplifies a wave of manufacturing cuts as pharma moves to more high-value, specialised medicines
‘No deal’ Brexit guidance fails to reassure UK chemical industry
UK government issues guidance on chemical regulation and patent law if the UK leaves the EU without agreement
India moves to ban cocktail drugs
Government injunction on 328 fixed dose combinations is strongly opposed by manufacturers
Landmark China cancer drug full approval ‘first of a wave’
Chi-Med’s fruquintinib is a result of China’s evolving drug innovation and regulation
Europe opens gates to CAR-T
First two modified T-Cell cancer therapies approved in the EU, but prices may be prohibitive for public health systems
US court overturns plant safety rule delay
US approves first RNA interference drug
US government ordered to ban chlorpyrifos insecticide
Vaccine scandal and heart drug recall show China’s pharma struggles
Novartis exit from antibiotics a setback for race against resistance
Trump coaxes big promises from big pharma
Drugmaker blocks Nevada execution
Alvogen obtains a restraining order to delay US prisoner’s execution, saying Nevada state obtained its sedative midazolam via ‘subterfuge’
American chemical industry fights against US tariffs
$10bn cracker for China
J&J hit with bill for $4.7 billion in damages over talcum powder cancer link
J&J and the question of shadow research
Ube’s management pays for lax quality checks
Bayer–Monsanto merger momentum
US chemical safety agency wants Arkema disaster to spark real change
US sanctions threaten Iran–Europe petrochemical ties
US senators launch probe of Novartis’ payments to Trump lawyer
Trump lays out plan to slash drug costs
