Significant SARS-CoV-2 variants circulating around the world: origin, spread and phylodynamics

The Coronavirus Pandemic and the Future: Virology, Epidemiology, Translational Toxicology and Therapeutics

Source: © Royal Society of Chemistry

A compilation of SARS-CoV-2 variants intended to support the mapping of origin, spread and phylo-dynamics of the evolving virus to aid in constructing control policies

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Viruses pose an ever-present threat to mankind as witnessed recently in the COVID-19 pandemic caused by a divergent RNA virus named SARS-CoV-2. This virus has had a grave impact on the physical, mental and economical status of human beings by its own life-threatening etiology as well as by interrupting the regular healthcare services, travel commerce, education and many other societal sectors during the global lockdown.

All viruses undergo evolution over time which may or may not lead to increasing its infectivity or transmissibility in addition to resistance to drugs devised to parental/original strains. Thus, as expected. the SARS-CoV-2 virus has undergone mutation over time. In this book chapter, we have listed all significant variants of SARS-CoV-2 reported till February 2021, with their respective mutations and epidemiological statistics. We believe that this compilation will help in the mapping of origin, spread and phylo-dynamics of the evolving SARS-CoV-2 virus which may aid in constructing control policies.

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