In this special we are asking what has become of the ‘holy grails’ outlined in an issue of Accounts of Chemical Research a quarter of a century ago. The short answer is: a lot. Some have been obtained (depending on your point of view); many others are still there for the taking. But every case has its fair share of discoveries, disappointments, surprises and success.
We’ve talked to researchers working in these areas today and, where possible, with the original authors of the 1995 articles to give us a picture of just how far we’ve come and how much has changed. We also wanted to see whether the publication history of these topics had its own stories to tell, so we’ve trawled through the bibliometric data to find out about who works with whom, who cites whom and where the most cited papers come from.
In the first in our series looking at chemistry’s holy grails from 25 years ago we examine how matter can now be controlled at its most basic level
Enzymes are nature’s ultimate catalysts and chemists are now on the verge of making their own versions from scratch
Two of the editors of the Accounts of Chemical Research issue, a computational superconductor researcher and a leading science writer give us their views
What if most materials are superconductors under the right conditions, wonders José Flores-Livas