Method that yields oxygen-18-enriched alcohols set to bolster drug studies

An image showing the synthesis of 18O-labelled alcohols from unlabelled alcohols

Source: © Ross Denton/University of Nottingham

Mitsunobu-based protocol is simple alternative to limited and lengthy methods

A protocol that provides scientists with a simple way to synthesise oxygen-18-labelled primary, secondary and tertiary alcohols has been established by scientists in the UK. The method could be used to make molecules that scientists can use to probe reaction mechanisms and test