The drug developers fighting the antibiotic resistance problem
Andy Extance talks to the researchers innovating across different drug classes in the hunt to develop new treatments
Who will pay for new antibiotics?
Governments around the world are starting to consider alternative funding models and incentives for antibiotics. Katrina Megget asks if it is enough
Charting the rise in antimicrobial resistance
We look at the data behind antibiotic drug discovery and development, bacterial resistance and the financial problems with the current business model
How can we maintain the effectiveness of existing antimicrobials?
Reducing environmental pollution and tackling quality issues to stave off resistance
Antimicrobial resistance: Exploring the One Health perspective and wastewater monitoring
The challenges created by antimicrobial resistance are only set to grow. Join us to equip yourself with the most up-to-date facts and knowledge
Opinion
If the drugs don’t work
A world without antibiotics would be a terrifying place
Resistant to change
Curbing industrial practices that drive antimicrobial resistance needs tighter regulation and enforcement
Catching the citizen science bug
Involving the public in research tackling superbugs
Surviving in the war of all against all
Cancers and bacteria develop resistance to drugs in remarkably similar ways
Profiles
A force against fungi
With antifungal resistance on the rise, Leah Cowen’s lab wants to identify molecules that can capitalise on vulnerabilities in fungal pathogens
Sharing antimicrobial expertise with Parliament
Emily Stevenson is one of two interns working alongside Green Party peer, Baroness Natalie Bennett
Valerie Mizrahi: ‘There’s no control to the experiment of life’
The world-leading tuberculosis researcher on switching specialities and living in a racially divided nation
More on AMR
Antibiotic adjuvant designed to subvert bacterial defence mechanisms
Amphiphilic molecule helps obsolete antibiotics accumulate and act within bacteria
Letters: November 2023
Readers share how the Talent Project is supporting technicians, share a proposal for enhanced oil recovery, and more
From the Royal Society of Chemistry
Listen to the RSC’s podcast series on AMR
Series 3 of the Royal Society of Chemistry’s ‘Brought to you by chemistry’ podcast covers antimicrobial resistance over six episodes. Host Alex Lathbridge talks to guests including Alison Holmes (president of the International Society for Infectious Diseases), Kaamini Walia (India Council for Medical Research), Sally Davies (former UK Chief Medical Officer) – and ITV’s favourite GP, Hilary Jones.
Letters: October 2023
Readers discuss antibiotic challenges, muse about micrographs and remember Philip Eaton
Mapping antibiotic’s binding of its target points to way to give drugs the killer edge
Technique that creates a comprehensive catalogue of mutations in antibiotic’s target reveals how drugs might be improved
Synthetic peptide mimics can act as antivirals
Peptoids disrupt enveloped viruses’ lipid membranes as well as targeting fungi and bacteria
Revived Neanderthal and Denisovan peptides show antibiotic activity
Molecular-scale ‘Jurassic Park’ process could uncover new medicines
UK to invest £210 million in global effort to monitor antimicrobial resistance
Funds will support upgrades to laboratories and staff training
Ancient microbial natural products reconstructed from Neanderthal dental plaques
Palaeogenomic approach allows natural product researchers to ‘go back in time’
UK antibiotics supply chain stretched by surge in Strep A infections
Government enacts protocols to enable substitute treatments and recommends preventive prescriptions in severe cases
Teixobactin’s two pronged antibiotic attack mechanism revealed
Understanding of formation of deadly supramolecular structures could help build improved antimicrobials
Molecular machine drills holes in antibiotic-resistant bacteria killing them
Bacteria aren’t able to develop resistance against nanomotor’s deadly action
Breaking bacteria’s genetic silence to synthesise antibiotics that evade resistance
Prospecting in bacterial genomes offers hope in search for new antimicrobial drugs
UK takes subscription approach for new antibiotics
Decoupling payment from prescriptions helps preserve last-line antibiotics and encourage R&D
Extent of pharmaceutical pollution on every continent on Earth revealed
Largest study of its kind creates map of drug contamination hotspots