Scientist working on bacterial culture

Keeping tabs on contamination

Argentina’s contaminated fentanyl tragedy highlights challenges of generic drug supply

BASF team

BASF begins building huge industrial heat pump for low-carbon steam

When powered by renewable electricity, BASF says system will cut carbon emissions by up to 98%

Albert Bourla and Donald Trump

Trump steps up pharma tariff threat

Taxing branded drug imports could hit biotech innovators hardest

Container ship

EU export of pesticides banned in bloc continues to increase despite commitment to end practice

Investigation of export notifications reveals prohibited agrichemical exports has risen by 50%

Highlights

Pharmaceutical research

UK loses life sciences investment as pharma companies halt expansion plans

Industry seeks greater share of healthcare spending to support innovation

Vivergo protest

UK biofuels production collapsing in face of cheap imports

Bioethanol plants closing after US tariffs removed, while biodiesel faces competition from China

Medicines

Pharma sector jolted by unpredictable US tariffs policy

Firms face tough decisions amid Trump’s threatened taxes on pharmaceutical imports and ‘capricious’ approach to tariffs

Fentanyl protests - people holding placards

At least 51 deaths in Argentina linked to tainted medical fentanyl

Investigation reveals history of regulatory failures as pharmaceutical company faces criminal charges over Argentina’s deadliest drug contamination scandal

AI drug development

As AI-designed drug looks to pass final hurdle, will this tech change drug discovery forever?

AI-led drug for chronic lung disease set to enter phase 3 clinical trials, though experts remain divided on AI’s impact in pharma

An abstract image of proteins involved in targeted protein degradation set over a purple background

Developing a CITK protein degrader using the QuicTPD™ platform

Sponsored by

Join us on 18 November to learn about the latest technology to accelerate the design of cancer treatments

Scientist working on bacterial culture

Keeping tabs on contamination

Argentina’s contaminated fentanyl tragedy highlights challenges of generic drug supply

Albert Bourla and Donald Trump

Trump steps up pharma tariff threat

Taxing branded drug imports could hit biotech innovators hardest

Pfizer logo

Arvinas and Pfizer seek a new home for protein degrader drug

Companies offer bifunctional cancer drug vepdegestrant to new partners after disappointing trial results

Pfizer logo

Arvinas and Pfizer seek a new home for protein degrader drug

Companies offer bifunctional cancer drug vepdegestrant to new partners after disappointing trial results

Titanium dioxide loses EU carcinogen label after court ruling

EU products no longer have to carry warnings about cancer risk from inhalation

Indian chemist dies after methanol inhalation incident

Preliminary investigation highlights lack of protective equipment

Why has the EU banned a key chemical in gel nail products?

Trimethylbenzoyl diphenylphosphine oxide is a photo-initiator used to harden nail polish under UV light

Deadly fentanyl contamination exposes drug safety challenges

Bacterial contamination in medical fentanyl has killed at least 51 people in Argentina, highlighting pressures on generic drugmakers

At least 51 deaths in Argentina linked to tainted medical fentanyl

Investigation reveals history of regulatory failures as pharmaceutical company faces criminal charges over Argentina’s deadliest drug contamination scandal

Bingham Canyon

Unrecovered byproducts from US mines could meet the country’s demand for dozens of critical materials

Huge quantities of metals and other elements are discarded each year in mining waste

Drug production

Ten years on, pharma industry still testing for implausible alkyl sulfonate ester contaminants

Risk assessment for potential mutagenic side-products is still required by regulatory bodies, despite lack of evidence they form during drug production

Refinery

Polymer membrane separates hydrocarbons, offering alternative to distillation

Microporous membrane enables energy efficient chemical separations

Improving propylene synthesis using light-activated catalysis could cut emissions

Single-atom photocatalyst makes propylene at milder temperatures

Generative AI pipeline creates promising antimicrobial peptides

AI model extrapolates beyond training data to predict diverse antimicrobial structures

Far more drugs could be taken orally by formulating them with silica nanoparticles

Many more medicines could be made water soluble making taking them easier for patients

Mapping metabolite disturbances by drugs

High-throughput metabolomic profiling gives insight into unpredictable drug effects

Metal–organic framework captures carbon dioxide at industrially relevant temperatures

Material could improve energy efficiency of capturing carbon from industy’s exhaust gases

BASF team

BASF begins building huge industrial heat pump for low-carbon steam

When powered by renewable electricity, BASF says system will cut carbon emissions by up to 98%

Fatal incidents at chemical plants in the US, India and Norway

Hydrogen and acid explosions, a fluorochemicals plant gas leak and a heavy lifting incident claimed at least four lives

Indian chemist dies after methanol inhalation incident

Preliminary investigation highlights lack of protective equipment

India introduces new rules to tackle chemical contamination sites

New legislation provides a legal framework for assessment and cleanup of 189 named chemicals

Chemours ordered to immediately limit PFAS emissions into Ohio River

US judge grants injunction to reduce Gen-X discharges from West Virginia plant to permitted levels

DuPont and spin-offs settle with New Jersey over PFAS contamination

Proposed deal with the US state includes $875 million in damages, plus clean-up funds

Sanofi

Sanofi to buy Blueprint Medicines for over $9 billion

Blueprint has one approved drug and enhances Sanofi’s immunology portfolio

Merck signage in Darmstadt

Merck KGaA to buy cancer specialist SpringWorks

$3.9 billion deal boosts Merck’s pipeline as it faces patent expiries

Thermal ellipsoid plot of the AdQPhos ligand

AdQPhos: Exceptional performance in α‑arylation reactions

Sponsored by

Download now to discover a more efficient and greener palladium cross-coupling catalyst

Cell culture in laboratory

Optimise drug discovery: predicting transporter-mediated drug interactions

Sponsored by

Learn how in vitro models, biomarkers and modelling can improve prediction of drug interactions and toxicity – reducing false positives and unnecessary clinical studies

Materials analysis concept image from Anton Parr

Pass or fail: rapid polymer analysis with FTIR

Sponsored by

Your guide to quick and reliable verification of polymers with the Lyza 7000 FTIR spectrometer