Headlines

Pumpjacks in an oilfield at sunset

Oil and gas industry emissions are not on track to hit climate goals

Several big firms have rolled back their targets, saying governments need to set pace with policy

person in a white shirt with a beard and glasses places a blue pipette rack next to some others. To their right a grid of pipettes dangles down from a liquid dispensing robot

Inertia, decisions and robots

Our cognitive biases can make it difficult to choose what’s best for science

East Palestine derailment

Rail company will pay $600 million to settle East Palestine lawsuits

Norfolk Southern reaches agreement to resolve litigation related to last year’s train derailment that spilled hazardous chemical cargo

Ritonavir

Could mechanochemistry have saved Abbott Laboratories $250 million?

Ball milling solves problem of disappearing ritonavir polymorph

Features

Industry

Industry’s water sustainability crisis

As the chemical industry decarbonises, will it require more water? Angeli Mehta looks at whether there is enough to go round

AMR

The drug developers fighting the antibiotic resistance problem

Andy Extance talks to the researchers innovating across different drug classes in the hunt to develop new treatments 

Cost of antibiotics

Who will pay for new antibiotics?

Governments around the world are starting to consider alternative funding models and incentives for antibiotics. Katrina Megget asks if it is enough

Golden-age

Charting the rise in antimicrobial resistance

We look at the data behind antibiotic drug discovery and development, bacterial resistance and the financial problems with the current business model

Ammonia

Fixing nitrogen fixing

Green ammonia promises a more sustainable future. Jamie Durrani talks to the researchers aiming to revolutionise the production of crucial fertiliser

Ritonavir

Could mechanochemistry have saved Abbott Laboratories $250 million?

Ball milling solves problem of disappearing ritonavir polymorph

Explosion

Six dead in explosion and fire at Indian pharmaceutical plant

At least 17 others injured at SB Organics facility near Hyderabad

Clouds reflection

Water isn’t normal

Despite its familiarity, water is a chemical oddity. But that’s what makes it fascinating

A sign in English and Chinese for Wuxi AppTec on the side of a office block

US government moves to block Chinese biotechs’ operations

WuXi Apptec and others accused of national security risk, as trade groups back legislation limiting their activities

Pumpjacks in an oilfield at sunset

Oil and gas industry emissions are not on track to hit climate goals

Several big firms have rolled back their targets, saying governments need to set pace with policy

US finally gets nationwide regulation of PFAS in drinking water

Long-awaited rule is significantly stricter and covers six PFAS, with a five-year phase in for water utilities

EPA’s clean air rule cuts chemical plant pollution

New regulation affects about 200 facilities in the US, reducing emissions of ethylene oxide, chloroprene and three other chemicals

3M finalises PFAS settlement with US water suppliers

Court-approved scheme will see up to $12.5 billion to fund cleanup of public drinking water systems

Chemours suspends chief and senior executives over accounting issues

Auditors to investigate issues around whistleblowing and financial management

From one sinking ship to another?

Biogen abandoning Alzheimer’s antibody aducanumab is unusual, but hardly surprising, says Derek Lowe

Ritonavir

Could mechanochemistry have saved Abbott Laboratories $250 million?

Ball milling solves problem of disappearing ritonavir polymorph

Dry cleaning

Photochemistry converts dry-cleaning solvent waste into useful chemicals

One-pot reaction offers way to upcycle industrial solvent waste

Laser

Lasers and lithium team up for ammonia production at ambient conditions

A pioneering method uses lasers and lithium salts to fix nitrogen with record-breaking yields

Electrochemical conversion of acids to alkenes achieved on kilogram scale

Efficient production of valuable alkenes achieved under mild conditions by reversing hydrocarboxylation reaction

Chemical industry hasn’t yet developed an appetite for biocatalysis, survey finds

Misconceptions along with a lack of time and resources driving industry’s reluctant attitude to biocatalysis and chemoenzymatic catalysis

Mechanochemical process makes fluorochemicals without HF

New approach brings safety and sustainability benefits

AI can suggest Covid-19 antivirals from protein sequence alone

IBM model can also find molecules that bind at different sites on target proteins

Colour-changing liquids could flag cold chain breaches for medicines

Device offers simple and reliable monitoring with no electronic waste

Newsletters

Tap water

3M finalises PFAS settlement with US water suppliers

Court-approved scheme will see up to $12.5 billion to fund cleanup of public drinking water systems

Chemours sacks top executives following accounting probe

Review found officers manipulated cashflow to hit targets and affect bonus payments

Chemours suspends chief and senior executives over accounting issues

Auditors to investigate issues around whistleblowing and financial management

Making chemicals safe and sustainable

The green transition is an opportunity to also make industry simpler and safer

Sustainability – from dirty word to industry imperative

Efforts to reduce the environmental impact of chemical processes have shaped the evolution of the entire sector

UN human rights experts condemn DuPont and Chemours

PFAS discharges from US plant denied community access to safe water, UN advisors assert

Drug manufacturing

Novo Holdings to buy contract manufacturer Catalent for $16.5 billion

Parent firm will then sell on three manufacturing sites to Novo Nordisk to boost capacity for diabetes and weight loss drugs

Grail

Illumina to give up Grail as competition appeals fail

Sequencing giant will sell off its former spin-out in accordance with regulator orders

Fracking in California

Chemicals roundup 2023

Chemical companies entered cost-cutting mode in a year dominated by overcapacity and slow demand

Joe Biden

Pharmaceuticals roundup 2023

Regulatory and pricing reforms have topped industry agendas in 2023, while weight loss drugs surged and Covid-19 therapies waned

Index

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