Headlines

Highlights

DDT collage

How DDT went from triumph to tragedy

Few compounds have a story as controversial as this insecticide. Mike Sutton traces the tale from its beginning 150 years ago

Industry

Industry’s water sustainability crisis

As the chemical industry decarbonises, will it require more water? Angeli Mehta looks at whether there is enough to go round

AMR

The drug developers fighting the antibiotic resistance problem

Andy Extance talks to the researchers innovating across different drug classes in the hunt to develop new treatments 

Cost of antibiotics

Who will pay for new antibiotics?

Governments around the world are starting to consider alternative funding models and incentives for antibiotics. Katrina Megget asks if it is enough

Golden-age

Charting the rise in antimicrobial resistance

We look at the data behind antibiotic drug discovery and development, bacterial resistance and the financial problems with the current business model

DCM

Ban on most uses of dichloromethane finalised in US

New rule phases out consumer use of the chemical within a year, and prohibits most industrial and commercial uses within two years

Oil and gas industry emissions are not on track to hit climate goals

Several big firms have rolled back their targets, saying governments need to set pace with policy

US finally gets nationwide regulation of PFAS in drinking water

Long-awaited rule is significantly stricter and covers six PFAS, with a five-year phase in for water utilities

EPA’s clean air rule cuts chemical plant pollution

New regulation affects about 200 facilities in the US, reducing emissions of ethylene oxide, chloroprene and three other chemicals

3M finalises PFAS settlement with US water suppliers

Court-approved scheme will see up to $12.5 billion to fund cleanup of public drinking water systems

Chemours suspends chief and senior executives over accounting issues

Auditors to investigate issues around whistleblowing and financial management

Scheme

Simplified hydroformylation replaces rhodium with base metal

Bench-friendly asymmetric hydroformylation swaps toxic gas and expensive catalyst for cheap reagents and mild conditions

Ritonavir

Could mechanochemistry have saved Abbott Laboratories $250 million?

Ball milling solves problem of disappearing ritonavir polymorph

Dry cleaning

Photochemistry converts dry-cleaning solvent waste into useful chemicals

One-pot reaction offers way to upcycle industrial solvent waste

Lasers and lithium team up for ammonia production at ambient conditions

A pioneering method uses lasers and lithium salts to fix nitrogen with record-breaking yields

Electrochemical conversion of acids to alkenes achieved on kilogram scale

Efficient production of valuable alkenes achieved under mild conditions by reversing hydrocarboxylation reaction

Chemical industry hasn’t yet developed an appetite for biocatalysis, survey finds

Misconceptions along with a lack of time and resources driving industry’s reluctant attitude to biocatalysis and chemoenzymatic catalysis

Mechanochemical process makes fluorochemicals without HF

New approach brings safety and sustainability benefits

AI can suggest Covid-19 antivirals from protein sequence alone

IBM model can also find molecules that bind at different sites on target proteins

Newsletters

Tap water

3M finalises PFAS settlement with US water suppliers

Court-approved scheme will see up to $12.5 billion to fund cleanup of public drinking water systems

Chemours sacks top executives following accounting probe

Review found officers manipulated cashflow to hit targets and affect bonus payments

Chemours suspends chief and senior executives over accounting issues

Auditors to investigate issues around whistleblowing and financial management

Making chemicals safe and sustainable

The green transition is an opportunity to also make industry simpler and safer

Sustainability – from dirty word to industry imperative

Efforts to reduce the environmental impact of chemical processes have shaped the evolution of the entire sector

UN human rights experts condemn DuPont and Chemours

PFAS discharges from US plant denied community access to safe water, UN advisors assert

Drug manufacturing

Novo Holdings to buy contract manufacturer Catalent for $16.5 billion

Parent firm will then sell on three manufacturing sites to Novo Nordisk to boost capacity for diabetes and weight loss drugs

Grail

Illumina to give up Grail as competition appeals fail

Sequencing giant will sell off its former spin-out in accordance with regulator orders

Fracking in California

Chemicals roundup 2023

Chemical companies entered cost-cutting mode in a year dominated by overcapacity and slow demand

Joe Biden

Pharmaceuticals roundup 2023

Regulatory and pricing reforms have topped industry agendas in 2023, while weight loss drugs surged and Covid-19 therapies waned

Index

From R&D to QC, making NMR accessible for everyone

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