3D printing deep in the body using ultrasound could deliver drugs, heal wounds
Biocompatible inks allowed polymers to be printed in animals without harming them
Snuff tube residues push back date of oldest hallucinogen use in Peruvian Andes
Chemical analysis reveals traces of a number of psychoactive compounds thought to have been used to secure leaders’ status
Glycoconjugate-caged drugs offer better way to treat inflammatory bowel disease
Plant fibres trap drugs, only releasing them in the lower intestine where they are more effective
Bridging the gap between Hammett parameters and the electronic structure of aromatic systems
Occupation of effective atomic orbitals used to quantify and predict Hammett parameters
Engineered microbe could clean up persistent oil pollution hotspots
First planar annulene compounds with metal centres synthesised
Filter paper simplifies squaramide synthesis
AI predicts transition states with exceptional precision
Skeletal editing provides quick access to pharmaceutical ‘matching pairs’
Charged droplets don’t splash when they hit a solid surface
Highlights
Fixing medicine’s gender gap
For centuries, the default subject in medicine research and training has been the male. Julia Robinson talks to the scientists and clinicians trying to improve things for the other 51% of humanity
How safe and sustainable are period products?
Millions of people around the world use period products every month. Bárbara Pinho finds out what their environmental footprint is and whether they carry chemicals harmful to human health
Managing the menopause
The end of ovulation will affect almost all women, but current treatments could be improved. Rachel Brazil reports on the efforts to find a better solution
What happens to our bodies after we die?
The decay and decomposition of a human body may be unpleasant to consider, but it can be crucial in criminal justice. Rupali Dabas talks to the forensic scientists developing techniques that can sniff out the truth
Crystal clear structure prediction
As the clouds clear on computational crystal structure prediction, is the technique ready to empower mainstream materials research? James Mitchell Crow reports
Topics
Bridging the gap between Hammett parameters and the electronic structure of aromatic systems
Occupation of effective atomic orbitals used to quantify and predict Hammett parameters
AI predicts transition states with exceptional precision
Model can complete tasks in under a second that take conventional methods hours
Accelerating chemical discovery through high-throughput experimentation: in conversation with Matthew Gaunt
Professor Matthew Gaunt from the University of Cambridge shares his thoughts on HTE and the role of automation and computational models in discovering new chemical space.
Amino acid sequences used to predict enzyme stereoselectivity
AI inspired by AlphaFold can predict chromatin structures found in chromosomes
Computational study says nucleophile finds σ-holes more attractive than π-holes
Computer simulations shed light on how material can shrink when heated
Simulations suggest why highly unsaturated molecules are so abundant in the interstellar medium
Snuff tube residues push back date of oldest hallucinogen use in Peruvian Andes
Chemical analysis reveals traces of a number of psychoactive compounds thought to have been used to secure leaders’ status
After-school club students in Chicago discover promising bioactive compound via goose droppings
Chicago antibiotic discovery lab engages middle school students from underrepresented communities in hands-on research
Chemists use AI to uncover pigments used on Berlin Wall murals
Researchers hope work will help to preserve this art
Teaching enzymes new reactions through genetic code expansion and directed evolution
Anthony Green’s research group at the University of Manchester, UK, reengineers enzymes to have catalytic functions beyond those found in nature
Filter paper simplifies squaramide synthesis
Capillary-driven flow distributes reagents evenly
Seed oil-based polymer should survive a day in the rain but degrade within years in the sea
Researchers create polyesteramides from brassylic acid and explore their potential as a replacement for polyethylene
Paul Anastas: ‘I’m proudest of being part of a global green chemistry community’
The father of green chemistry on his love of the environment, striving for unattainable perfection and breathing life into an old town library
Redox reactions ‘mine’ old fluorescent light bulbs for europium
In just three simple steps rare earth element can be recovered, avoiding ‘ecologically devastating’ mining
ERC increases funding offer to support scientists moving to Europe
Move is part of global efforts to attract researchers dismayed by the funding chaos in the US
Eight companies are selling authorships of UK ‘design patents’
Majority of registrations sold go to Indian researchers to pad CVs and bolster promotion chances
Universities and academic groups join forces to fend off Trump’s attacks
Legal actions are thwarting White House attempts to pull funding from top research universities and terminate international student visas
Under legal pressure American Chemical Society ends diversity programme
The society is replacing its 30-year-old Scholars Program for minorities with a larger one that does not consider race
Materials scientist’s death at 47 from brain haemorrhage highlights long hours culture in China
Liu Yongfeng’s death isn’t the first instance of a Chinese academic with a heavy workload dying young