‘Chemists dismissed us as being too biologically focused’

An artificial imine reductase whose activity has been optimised by means of directed evolution

Source: © Martina Hestericova

How directed evolution winning the chemistry Nobel is going to change my field

Martina Hestericova considers how directed evolution and phage display winning the chemistry Nobel prize in 2018 will change the field she worked in for four and a half years earning a PhD. She now believes that recognition of her field will mean that scientists working in this area will no longer feel outsiders in the catalysis community. An explosion of research in directed evolution of enzymes is now expected with enzymes being harnessed to do all sorts of chemistry once thought too difficult for nature’s transformative Swiss army knives.