Enantioselective synthesis of elusive chiral nitrogen compounds discovered by chance

An ‘elegant and simple’ way to make nitrogen stereocentres by supramolecular recognition

Researchers from Durham University, UK, have discovered a simple way to make chiral nitrogen structures as single mirror image molecules. This first enantioselective synthesis of ammonium cations makes such stable nitrogen stereocentres easily accessible – something that so far had been only possible using certain natural compounds.