Researchers add to growing toolkit of bifunctional reagents
A new bifunctional reagent allows chemists to install a fluoroalkyl group while simultaneously attaching an azide click handle.1
Click chemistry is a powerful and efficient approach to preparing complex molecules through selective and high yielding reactions that work with many different types of substrates. The classic version combines an azide and an alkyne. However, before chemists can perform such reactions, the molecules they want to join must first have the appropriate functional groups.