It’s that time of year again: offices, labs and departments are slowing down for the holidays. To keep you entertained and inspired over the festive period, the Chemistry World team has selected some of our favourite stories from 2025.
The articles below include long reads covering fascinating areas of chemical research, important news stories, top tips for achieving your career goals, and much more.
As multiple novel male contraception compounds enter clinical trials, is family planning about to undergo a second revolution? James Mitchell Crow reports
Read storyClaims of an AI revolution in drug discovery are missing the biggest problem
Screaming fans excited about your research, the Sharpie on your lanyard for signing autographs – wouldn’t that be nice?
‘Ingenious and creative solution’ to electrochemistry’s ‘horrible wiring problem’
Where else do you get such an opportunity to tinker with things?
Read storyComputer-designed enzyme competitive with nature for the first time
One-time gymnast Melanie Sanford has made a name for herself in catalysis and organometallic chemistry. Rebecca Trager charts her path to success, from her mentors to her mentoring
Fake news about assassinated scientists was ‘disturbing and distressing’ for targets
Creativity has been central to James Shee’s career across both art and science
Read storyRebecca Trager catches up with four chemists to see how their working lives have changed since the start of the Covid-19 pandemic
Fermentation can improve sustainability at competitive costs
The EU has recently approved the use of glyphosate for another decade. Bárbara Pinho examines the controversial pesticide’s presence in British farming and considers the possibility of a ban in the UK
The decay and decomposition of a human body may be unpleasant to consider, but it can be crucial in criminal justice. Rupali Dabas talks to the forensic scientists developing techniques that can sniff out the truth
Read storyResearchers say controversial policy will block majority of scientists from applying for grants
New wave of precision medicines amplify or silence genes, without altering genetic code
Finding ways to fund students as they search for jobs and complete lab work for publications
Late-stage functional group switching in dibenzofurans will aid drug discovery chemistry
Millions of people around the world use period products every month. Bárbara Pinho finds out what their environmental footprint is and whether they carry chemicals harmful to human health
Chemistry World talks to Ryo Horikoshi about engaging students with chemistry concepts using his stunning paper models
Researchers around the world have faced a tough year as many countries have frozen or even cut funding, but despite these pressures there has still been plenty of exciting science on show as AI and machine learning continue to make waves in the field.
The stories that dominated the news this year
The research that has amazed and amused us this year
Geopolitical turbulence has rocked both pharmaceuticals and chemicals industries this year, with trade tariffs and regulatory upheaval in pharmaceuticals, while nationalist growth strategies in China and elsewhere have exacerbated pressure on chemicals producers - particularly in Europe.
Valentine Ananikov explains how the humble stirrer bar may be altering your results
Read storyDRC government is intervening to revive prices and stabilise supply chains
100 years ago, Cecilia Payne deduced that the sun is mainly made of hydrogen – but was encouraged to downplay her findings by her PhD supervisor. Mike Sutton takes up the story
As we celebrate the anniversary of benzene’s isolation, we must remember that scientific centenaries carry additional agendas
Sabic will not reopen UK plant and Dow will close another in Germany
Read storyA ferrocene-derived complex is a further exception to the 18-electron rule
A five-step approach to present effectively
Contentious study continues to make waves as authors and researchers argue over whether action is proportionate and beneficial
Analytical chemistry can tell us what our ancestors ate thousands – or even millions – of years ago. Rachel Brazil gets her teeth into the evidence
Read storyA heating device from a fan of heated disputes
Four steps to assess your current position and set your goals
Companies are racing to develop alternatives to injectable diabetes and weight loss drugs
The scientists using visual storytelling to communicate their work – and how you can do it too
Read storyBioethanol plants closing after US tariffs removed, while biodiesel faces competition from China
The unusual concoctions of village witches have historically been dismissed as nonsense hocus pocus – but is this the whole story? Victoria Atkinson investigates the chemistry behind the myth and whether there was more to witchcraft than ritual and superstition
Despite its low cost and low toxicity, bismuth has found limited applications in organic synthesis. Liam Ball is working to change that
From wooden models to thousands and thousands of structures, Julia Robinson tells the story of how Richard Robson, Susumu Kitagawa and Omar Yaghi won the 2025 Nobel prize in chemistry
Read storyThe benefits and challenges of returning to academia after a period away
Augmented pentalene structure could be a molecular Schrödinger’s cat, aromatic and antiaromatic at the same time
AIs like Microsoft’s Copilot, Google’s Gemini and OpenAI’s ChatGPT still make serious errors rendering structural formulae
In Portugal’s Douro valley, centuries-old winemaking traditions meet modern chemistry to create a sweet and intense fortified wine. Bárbara Pinho talks to the experts about the compounds and reactions behind a festive favourite
Read storyHosting visitors is fun and requires a lot of preparation
University of Nebraska’s drug design centre director is communicating his team’s scientific breakthroughs with tattoos and now has 29 on his arm
Two new strategies tackle Fischer–Tropsch’s problematic side reactions
While scientific publishing is far more open than when the consortium launched seven years ago, it is still far more closed than it was aiming for
Read storyOnce-magical tools are now mundane. What will the next miracles be?
An abusive lab member made my dream course a nightmare. By speaking up, I’m reclaiming my joy
RRS Sir David Attenborough scientists are trying to measure the potentially crucial role of ocean manganese, finds Andy Extance. But how do you do cutting-edge science in the inhospitable Southern Ocean?