Troubleshooting contamination in LC-MS systems: An at-a-glance guide for chemists
There are many common background contamination ions encountered in mass spectrometry, including polyethylene glycol, polypropylene glycol, phthalates, organic solvent clusters, solvent modifiers, fatty acids, metal ions, tritons, tweens and siloxanes. Metal ions can also form adducts with varying numbers of substrates to give characteristic ESI+ ions. This can make identifying contaminants challenging and waste your time in the lab.
This free poster from Thermo Scientific Chemicals includes the accurate mass of elements, organic solvents and all potential contaminant ions observed in mass spectrometry to help chemists troubleshoot potential contamination in LC-MS systems.