Industrial chemistry – Page 5
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OpinionBeyond buckets and batches
Embracing flow chemistry means leaving behind some faithful friends
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FeatureCO2 recycling – an uphill struggle
James Mitchell Crow explains how chemists are turning a problematic greenhouse gas into commercially useful molecules, at industrial scale
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PodcastPhosphorus chlorides
A hugely useful group of compounds that have a distinct dual personality
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Podcasttert-Butyl lithium or t-BuLi
A pyrophoric reagent that remains one of chemistry’s staples and the liquid salts that can tame its wild reactivity
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PodcastChlorine trifluoride
Tabitha Watson introduces a poisonous, corrosive and extremely reactive compound that will start ‘roaring reactions’ with almost anything
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OpinionMake room for randomness in drug development
Setting free the dark horses sometimes beats the most rational planning
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OpinionWhat's holding back continuous manufacturing?
Despite manay advantages, the move to flow chemistry in fine and speciality chemicals is slow
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ResearchLilly pushes continuous drug production limits
Integrated flow synthesis and purification process for prexasertib meets high industry standards
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BusinessMerck KGaA to buy Chematica
Retrosynthesis tool will gain computational muscle and integrate with Sigma–Aldrich catalogue
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OpinionCrystal clear
The dark craft of crystallisation is an essential skill when working on kilogram scale
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FeatureThe flow revolution
Continuous approaches are starting to find use in fine chemicals, as Angeli Mehta discovers
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ResearchTamed radicals expand chemical space
A method to functionalise complex molecules with catalytic radicals could expand chemical libraries of the drug and agrochemical industry
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ResearchZeolite catalysts tailored to specific chemical reactions
Molecules that mimic shapes of transition states of important industrial reactions help to build better catalysts
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OpinionIn search of solvation
Process chemistry opens up a whole new world when it comes to solvent choice
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OpinionStill boiling after all these years
If you’ve got the facilities, distillation can be a powerful plant technique
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ResearchRing-locking holds the key to levoglucosan production
Functionalising sugars could help to unlock the potential of biomass in chemical synthesis
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ResearchMembrane reactor turns methane into aromatics
Catalytic technology could turn untapped hydrocarbons into valuable chemical feedstocks