New class of antifungals show potent effects against priority pathogens

Voriconazole

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Coniotins, found in another fungus, is effective against drug-resistant pathogenic fungi

A previously uncharacterised class of antifungals that is effective against several critical fungal pathogens has been discovered.

The researchers at McMaster University in Canada demonstrated a novel platform for antifungal discovery using prefractionation – a method that allows for specific molecules to be teased out from complex chemical mixtures – to screen for, and uncover, previously overlooked bioactive compounds.