Thianthrenium reagent captures elusive protein interactions in living cells
By 
Ada McVean2025-12-19T09:29:00
Reagent creates short, stable protein crosslinks, enabling researchers to identify previously unknown protein–protein interactions
A new thianthrenium reagent creates short, stable protein crosslinks that will help identify rarer protein–protein interactions in cells. ‘We have invented new chemistry that can afford answers to questions that could not be asked before with the chemistry that was available,’ says Tobias Ritter of the Max-Planck Institute for Coal Research in Germany, who led the work.