Tool for designer disordered proteins unentangles their function

Tangled wires

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Mysterious structure–function relationship of intrinsically disordered proteins probed by machine-learning platform

A new computational tool can design disordered proteins and decipher their function. The work could help scientists unravel the mysterious sequence–function relationship of intrinsically disordered protein regions, which exist in 70% of human proteins and are thought to have critical roles in the body, including disease.