All intermediates articles
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ResearchSeventy-year search for simpler route to valuable reactive intermediate ends
Ortho-quinodimethane made under mild conditions from common reagents
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ResearchForce-sensitive molecule pulled apart to create highly reactive aryne
High-intensity ultrasound initiates formal retro-[2+2] cycloaddition by stretching a benzocyclobutene core from strategically placed anchor points
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ResearchElectrophilic aromatic bromination study casts doubt on textbook intermediate
New computational evidence that electrophilic aromatic bromination actually occurs via an addition–elimination mechanism
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OpinionSpace, energy and synthetic half-reactions
Matching driving forces with intermediates to predict new chemistry
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ResearchTextbook aromatic substitution mechanism overthrown
Established intermediate in nucleophilic aromatic substitution found to be a rare exception rather than the rule
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ResearchReactive intermediates tamed in natural product synthesis
Benzynes perform remarkably selective reactions with natural products that lead to uniquely complex compounds