Clinical trials
The latest chemistry news and research on clinical trials, including regulatory approval, trial safety and ethics, from the Royal Society of Chemistry's magazine, Chemistry World
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FeatureNew treatments offer hope for neglected snakebite victims
Nina Notman meets the scientists developing recombinant antivenoms and small molecule inhibitors to save the lives and limbs of snakebite patients, who number in the their hundreds of thousands
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OpinionModerna’s vaccine regulatory hokey-cokey
US FDA initially refused to accept flu vaccine for review, but has since reversed that decision
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ResearchWorld first for clinical trial of skin patch to monitor therapeutic drugs in real time
Sensor could soon help doctors to prevent overdoses of drugs
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NewsIn 2023, the UK was the first country to approve a Crispr therapy. How’s it doing?
Disconnect exists between the media hype around gene-editing treatment and the reality for patients
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NewsNew £50 million centre aims to shake up clinical trials in the UK
Initiative should speed up testing of new medicines
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NewsCould Crispr cure HIV?
The first gene-editing therapies for HIV/Aids are entering trials but the virus is proving once again that it is a master at evading eradication
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BusinessArvinas and Pfizer seek a new home for protein degrader drug
Companies offer bifunctional cancer drug vepdegestrant to new partners after disappointing trial results
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NewsCan a bowl of tomato soup a day keep the winter blues away?
Human trial to test whether gene-edited tomatoes can boost participants’ vitamin D levels
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NewsAs AI-designed drug looks to pass final hurdle, will this tech change drug discovery forever?
AI-led drug for chronic lung disease set to enter phase 3 clinical trials, though experts remain divided on AI’s impact in pharma
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OpinionIgnoring women’s health shouldn’t be an option
Developing therapies for conditions that predominantly affect women is a neglected, but enormous, opportunity
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OpinionWomen are not just another confounding factor in drug development
Ignoring physiological differences between the sexes is indefensible
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OpinionIn search of truth and rules
To codify and predict ever more complex phenomena is one of science’s great drivers
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NewsFears grow over the future of mRNA vaccine research in the US
Researchers working on mRNA vaccines fear federal funding might be halted, with many looking to move projects abroad
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BusinessEpigenetic editors enter clinical trials
New wave of precision medicines amplify or silence genes, without altering genetic code
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OpinionRobots queuing up to fail
Claims of an AI revolution in drug discovery are missing the biggest problem
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BusinessUS approves schizophrenia drug with new mode of action
Cobenfy promises to better address negative symptoms than existing antipsychotics
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BusinessMDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
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BusinessBig deals confirm renewed interest in radiopharmaceuticals
Acquisitions of RayzeBio and Point Biopharma highlight the potential of targeting radioactivity directly to tumour cells
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BusinessNew Covid-19 antiviral cuts symptoms by 1.5 days
Simnotrelvir already has emergency approval in China
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BusinessWeight-loss drug shortages prompt copycats and counterfeits
Novo Nordisk and Eli Lilly have struggled to meet huge demand for new hormone mimic obesity treatments