Clinical trials
The latest chemistry news and research on clinical trials, including regulatory approval, trial safety and ethics, from the Royal Society of Chemistry's magazine, Chemistry World
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News
Fears grow over the future of mRNA vaccine research in the US
Researchers working on mRNA vaccines fear federal funding might be halted, with many looking to move projects abroad
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Business
Epigenetic editors enter clinical trials
New wave of precision medicines amplify or silence genes, without altering genetic code
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Opinion
Robots queuing up to fail
Claims of an AI revolution in drug discovery are missing the biggest problem
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Business
US approves schizophrenia drug with new mode of action
Cobenfy promises to better address negative symptoms than existing antipsychotics
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Business
MDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
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Business
Big deals confirm renewed interest in radiopharmaceuticals
Acquisitions of RayzeBio and Point Biopharma highlight the potential of targeting radioactivity directly to tumour cells
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Business
New Covid-19 antiviral cuts symptoms by 1.5 days
Simnotrelvir already has emergency approval in China
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Business
Weight-loss drug shortages prompt copycats and counterfeits
Novo Nordisk and Eli Lilly have struggled to meet huge demand for new hormone mimic obesity treatments
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Business
Positive trial sets stage for therapeutic use of MDMA in US
Hallucinogen-assisted psychiatric treatment heads to regulators, amid cost and other concerns
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Business
Alzheimer’s antibody engenders anticipation
Tantalising press-released data on Biogen and Eisai’s lecanemab prompt questions without firm answers
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Opinion
May cause side effects
The dose makes the poison, but understanding unwanted drug interactions is complicated
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Opinion
Alzheimer’s, amyloid and abandoned antibodies
Biogen’s aducanumab is stumbling into obscurity. Where does that leave the amyloid hypothesis?
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News
New questions raised over Sputnik Covid vaccine results point to fraudulent practices
Analysis comparing Sputnik results with five other Covid vaccines finds phase 3 trial outcome is highly improbable
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Business
What is the future of Covid-19 pharmaceuticals?
Firms anticipate long-term markets for prevention and treatment
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Business
Trials start of mRNA vaccine for HIV
First steps towards protection from the many and variable viral strains
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Research
Engineered antibody that snags sperm could be an effective non-hormonal contraceptive
Approach could offer new method of contraception for women
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Business
Covid-19 antivirals surge forward
Promising results from Pfizer trial, while UK approves Merck & Co’s molnupiravir
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News
Hints that century-old TB vaccine offers an immune boost against Covid-19
Small study is part of global effort examining whether the BCG jab could help in the next pandemic
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News
Promotion of Covid-19 pseudoscience by Indian government criticised as pandemic rages
Questionable therapies under study or promoted include prayer, breathing exercises and herbal medicines
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Opinion
The side effects of being unique
Even the largest clinical trials won’t capture all possible bad reactions to a drug – we need pharmacovigilance