Clinical trials – Page 3
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OpinionAre new drugs better than existing ones?
Should companies be made to change the way they run clinical trials?
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BusinessCleaning up clinical trials
Campaigns to enforce complete and correct reporting of trial data are beginning to take hold
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NewsTracker to name and shame for failure to report clinical trial results
Developers of online tool hope that it will improve accountability
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BusinessCall for overhaul of EU rules on GMO clinical trial
Rules designed around genetically modified plants crops are holding back new cell and gene-based medicines
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FeatureThe long road to an HIV vaccine
A vaccine may not be available anytime soon, but its proponents are hard at work
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BusinessAstraZeneca shares tumble after antibody failure
Imfinzi and tremelimumab checkpoint inhibitor pairing fails to beat chemotherapy in lung cancer
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ResearchLilly pushes continuous drug production limits
Integrated flow synthesis and purification process for prexasertib meets high industry standards
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OpinionUnpicking a clinical trial death
A new study shows up off-target effects of a drug that proved deadly, and highlights the pitfalls of drug discovery
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OpinionHow safe should drugs be?
What does spotting new risks in approved medicines say about how effective regulators are?
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ResearchCatalyst puts chiral twist on phosphorus drugs
Simple molecule overcomes headache of phosphorus stereochemistry in antiviral drug synthesis
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NewsFears that gene-editing cancer trials are premature
Warnings from geneticists that Crispr trial failures could knock promising technique’s prospects
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OpinionRegulatory tightropes
When lobbying and marketing clash with scientific evidence, regulators walk a fine line
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BusinessFDA urges labs to test all blood donations for Zika
Agency has also given emergency authorisation to two new Zika blood tests
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BusinessJuno CAR-T trial suspended after patient deaths
Immunotherapy study restarted with amended pre-treatment protocol
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News
Large HIV vaccine trial to launch in South Africa
US funding agency will enlist 5400 people for HIV vaccine study in South Africa in November
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NewsInsider trading scandal topples head of Taiwan’s top research body
President of umbrella organisation overseeing 24 research institutions caught up in investigation into offloading of biotech shares prior to poor results
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BusinessClinical trial death highlights hazards
Pain drug trial has left one dead and five hospitalised in France, with little indication as to the cause of the problems
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Business
EU regulator calls for generic drug suspensions
The EMA wants hundreds of formulations off the market after identifying systematic fraud in a major Indian contract clinical research organisation
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News
Tufts’ $2.6bn drug development figure questioned
Details sought about how university determined cost of bringing a drug to market jumped 145% since 2003
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NewsEbola vaccine passes first safety hurdle
Researchers hope to begin larger trials of its effectiveness in west Africa soon