Clinical trials – Page 3
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BusinessProtein-based Covid-19 vaccines could overshadow rivals
Although slower to develop, protein-based vaccines are well understood with a strong record of safety and effectiveness
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BusinessRussian vaccine launch shocks scientists
Sputnik V to be approved without large human trial data
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NewsDoes hydroxychloroquine still have a role to play in this pandemic?
Touted as a wonder drug by some its star now appears to be on the wane
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BusinessWhat are the risks of fast-tracking a Covid-19 vaccine?
Condensing timelines from years to months inevitably involves compromises
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NewsCovid-19 is forcing pharma to rethink clinical trials
Drug trials have become a casualty of Covid-19, but the pandemic is also prompting change
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OpinionHopes and fears for remdesivir
Available resources for testing coronavirus treatments need to be used wisely
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OpinionDoes the drug work, or not?
Coronavirus trials reveal the murky reality of disentangling compounds’ effects on human biology
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OpinionVaccine development against the clock
How long will it take to develop a coronavirus vaccine and why is it so hard?
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BusinessCan existing drugs slow Covid-19?
The fastest route to treatments may be to repurpose existing drugs – if they work
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BusinessSixth in a line of Alzheimer’s drugs fails in trials
Treatments designed to stop amyloid peptide formation all seem to cause cognitive impairment rather than prevent it
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OpinionAre new drugs better than existing ones?
Should companies be made to change the way they run clinical trials?
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BusinessCleaning up clinical trials
Campaigns to enforce complete and correct reporting of trial data are beginning to take hold
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NewsTracker to name and shame for failure to report clinical trial results
Developers of online tool hope that it will improve accountability
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BusinessCall for overhaul of EU rules on GMO clinical trial
Rules designed around genetically modified plants crops are holding back new cell and gene-based medicines
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FeatureThe long road to an HIV vaccine
A vaccine may not be available anytime soon, but its proponents are hard at work
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BusinessAstraZeneca shares tumble after antibody failure
Imfinzi and tremelimumab checkpoint inhibitor pairing fails to beat chemotherapy in lung cancer
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ResearchLilly pushes continuous drug production limits
Integrated flow synthesis and purification process for prexasertib meets high industry standards
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OpinionUnpicking a clinical trial death
A new study shows up off-target effects of a drug that proved deadly, and highlights the pitfalls of drug discovery