I read Derek Lowe's column every month and normally enjoy his observations on the world of medicinal chemistry, but his article 'The usual suspects' cannot go unchallenged.
He states: 'There's cisplatin for the entire set of metals, and that's about that.' Has he never heard of anaemia and drugs such as ferrous sulfate and ferrous gluconate which contain Fe2+ as the active ion?
He further states that phosphorus is in big osteoporosis drugs, but fails to mention the important anticancer agent, cyclophosphamide, which most certainly contains a P atom.
He also neglects boric acid in eye drops (the only acid you can safely put in your eye).
Sorry Derek. This piece isn't up to your usual high standard.
D Cairns CChem FRSC
Robert Gordon University, UK