All skeletal editing articles
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ResearchSimple reagent slices open phenol rings, converts them into various nitrogen-containing products
Strategy adds to the skeletal editing toolbox, creating flexible chains from flat arene rings
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ResearchMicrodroplet chemistry enables catalyst-free skeletal editing
Hydroxyl radicals power transformation of aniline into pyridine
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ResearchOne-step photochemical method switches nitrogen and carbon to convert pyrazoles into imidazoles
Transformation tolerates a broad range of functional groups while preserving the peripheral substitution of the heterocycle
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ResearchVersatile skeletal editing strategies upgrade nitrogen compounds into drug building blocks
Two techniques could help speed up the discovery of drugs containing nitrogen heterocycles
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ResearchPhotocatalytic skeletal editing technique migrates substituents to challenging meta-position
Meta-substituted aromatic rings are key structures in many drug molecules
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Research‘Stimulating discovery’ leads to strategy to swap oxygen in saturated rings
Skeletal editing pushed beyond aromatic structures, sparking new opportunities in drug discovery
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ResearchOne-pot atom swap chemistry allows direct indole-to-benzimidazole conversion
Industrial chemists set to benefit from addition to skeletal editing toolbox
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ResearchSkeletal editing provides quick access to pharmaceutical ‘matching pairs’
Late-stage functional group switching in dibenzofurans will aid drug discovery chemistry
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ResearchReimagining synthetic strategy with skeletal editing ticks box on chemists’ wish list
Selective heteroatom alkylation offers route to modify important drug building blocks
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ResearchSkeletal editing targets double bonds
Two new techniques selectively install nitrogen atoms into complex molecules
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ResearchSkeletal editing technique removes nitrogen atoms from rotaxanes
Reaction breaks and repairs a rotaxane’s axle without allowing its ring to slide off
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ResearchDesigner ylide transfers single carbon atoms
Single-atom carbon transfer reagent provides the latest breakthrough in skeletal editing
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ResearchRegioselective nitrogen-insertion reaction is latest addition to skeletal editing toolbox
Protocol transforms arenols into benzazepines
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ResearchSkeletal editing that simply swaps aromatic carbons for nitrogens will aid drug discovery
Atom-swapping chemistry gains two new techniques that are ready to use
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ResearchSmall ring insertion expands structural editing toolbox
Bicyclic ring system made by adding a bicyclobutane into a thiophene
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ResearchSkeletal editing provides a simple route to access isoquinolines
Direct nitrogen atom insertion into a broad range of indenes and cyclopentadienes
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