All substitution articles
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ResearchOrigin of mysterious alpha effect in nucleophilic substitution reactions unveiled
Alpha nucleophiles’ ability to get close to electrophiles – rather than their intramolecular lone pair repulsion – gives them unusual reactivity
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ResearchCatalyst cleans up alcohol couplings
Eight years’ work yields Mitsunobu chemistry with nothing but water as a byproduct
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WebinarFrom Reach compliance to innovation – making use of data and tools
The European Chemicals Agency presents how the wealth of information collected and generated under Reach and CLP can be used to make better choices for product development
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BusinessSafer substitutes show growth potential
The global market for alternative products based on ‘green’ chemistry is growing fast, fuelled by regulation and consumer demand
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BusinessUS pushes for global phase-out of HFCs
Executive actions and industry commitments aim to speed up adoption of alternatives to hydrofluorocarbon greenhouse gases in refrigeration and air conditioning
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Business
Data sharing helps firms reduce Reach animal testing
Alternative in vitro methods slowly gaining traction for some tests
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NewsRare element substitution a tricky proposition
Audit of scarce materials finds alternatives for use in modern technologies like computers and mobiles are even scarcer