All Synthetic biology articles
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ResearchLight-harvesting wheel reinvented by chemists copying bacterium
Synthetic mimic of complex at the heart of photosynthesis offers new ways to capture solar energy
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Research
Unnatural reaction benefits from computational tool that teaches an old enzyme new tricks
Method could generate artificial enzymes that are more suitable for directed evolution
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Research
Protein synthesis revolution on way as large peptides made in hours not days
Flow chemistry can now make peptide chains up to 164 amino acids long in one go
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Research
Unnatural cyclic amino acids push limits of ribosome
Expanding repertoire of monomers for ribosome-mediated polymerisation is boon for scientists wanting to harness nature’s protein factories
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Research
Photosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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Research
Artificial chloroplasts turn CO2 into multicarbon molecules, powered only by light
Microfluidic platform opens up non-natural metabolic pathways
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Research
Soap-like catalyst outperforms enzyme with mimicry and micelles
Bioinspired approach could be used for a range of enzymes
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Research
Engineered neurons synthesise their own conductive polymer coating
Cell-specific electric stimulation could help be used with bioelectronic prostheses or treat diseases like epilepsy
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Sponsored
Transforming innovation for startups
Green polymer specialists Novomer and biotech startup SynbiCite optimised industrial and biotech processes using design of experiment software from JMP
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Research
First Crispr cancer trial in humans shows safety and durability
Immune-cell modifications target tumours and lift the PD-1 ‘brake’
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Research
Giant, long-lived bacteria could make microbial farms more productive
Biochemical production could be boosted using Escherichia coli engineered to grow to 13 times their usual size
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Research
Bacterium forced to evolve to consume carbon dioxide to make biomass
Tweaked Escherichia coli could help deal with humanity’s carbon dioxide problem
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Research
Robotic system can plan and perform biosynthesis without human intervention
New strategy combines machine learning with automation and has proven itself optimising a complex biochemical pathway
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Research
Engineered cyanobacteria turn carbon dioxide into petrol substitute
Strategy transforms wild photosynthetic organism into a system that could reduce humanity’s reliance on fossil fuels
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Research
Semi-synthetic bacteria make designer proteins
E. coli with synthetic DNA bases produce unnatural proteins that could be used as drugs
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Opinion
What happens when life has a limited vocabulary?
The longest synthetic genome shows us life is more complicated than just learning your AGCs
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Research
Enzyme evolved to selectively functionalise carbon–hydrogen bonds
Lactam libraries created by engineered bacterial enzyme offer new way to fight antibiotic resistance
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Research
First bacterium with a totally redesigned genome created
Designer E. coli uses a simplified genetic code to make proteins
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Research
Radical route produces non-natural polymers inside cells
Strategy could enable scientists to manipulate, track and control cellular behaviour by generating macromolecules within cells
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Research
Transcription controlled by non-natural DNA modifications
Proof-of-concept for artificial chemical epigenetics
