Biology – Page 5
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Research
DNA-damaging device could make mutant discovery safer and simpler
Cool microplasma jets create a stream of radicals that induce mutations
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Business
UK becomes first country in the world to authorise a Crispr-based gene therapy
Treatment aims to cure patients with β-thalassaemia and sickle-cell disease
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News
Fisheries agency concludes it’s ‘very unlikely’ pyridine behind UK crustacean deaths after new tests
Cause of mass die-offs in late 2021 and early 2022 still a mystery
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Research
Synthetic yeast genome project creates strain with over 50% synthetic DNA
Entirely artificial organism opens up door to designer yeast with biotechnology applications
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Research
Underwater device reveals marine chemical diversity
I-Smel device probes metabolites produced by Mediterranean sponges
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Research
Painting with DNA
Fluorescently labeled DNA strands produce a palette of 16 million colours
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Research
Controlling insulin activity in cells with ‘DNA origami’
Insulin–DNA nanorods elicit geometry-dependent insulin activity, which could lead to more targeted treatments for diabetes
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Feature
Battling long Covid with drugs
The challenge of finding drugs for a poorly understood disease with many symptoms is clear. Clare Sansom looks at the work going on to help the people suffering in its shadow
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Research
ACE2 receptor not essential for Sars-CoV-2 infection, study shows
Fresh understanding linked to evolutionary plasticity of Covid-19 virus
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Research
Field study reveals banned pesticide sulfoxaflor had no effect on pollination by bumblebees
Work adds to nuanced picture of pesticide’s effect on pollinating insects
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Feature
Medical uses for silk
Nina Notman speaks to the researchers exploring medical applications for silkworm silk
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Research
Direct imaging reveals individual protein-bound glycans in new detail
Sequences and locations of biomolecule-bound sugar chains studied at the single-molecule level
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Research
Genetic-editing of chickens protects them from catching the flu
Approach heralds new way to make animals resistant to disease
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Opinion
Will the assembly theory imbroglio do anything for evolution?
A claim to have explained selection has caused a stir, and it’s worth asking why, says Philip Ball
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Research
Assembly theory puts chemistry centre stage to explain molecular complexity and life’s origins
Concept that attempts to join physics and biology via chemistry met with interest but also harsh criticism
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Opinion
Moving beyond protein structure
Efforts to understand how intrinsically disordered regions interact have produced a variety of answers
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Research
Mutation studies reveal how Antarctic octopus arms itself with cool enzyme
Understanding cold-tolerant enzyme could help with transplant organ preservation
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Research
Cryo-EM scaffold supports imaging of small proteins previously tricky to study
Improved understanding of the structure of small proteins could aid drug designers
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News
mRNA vaccine pioneers win medicine Nobel prize
Katalin Karikó and Drew Weissman honoured for breakthroughs that enable the rapid development of new vaccines, including several of those used against Covid-19
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Research
’This is just the beginning’: RNA editing set to democratise viral engineering
Crispr-based system could ease development of novel RNA therapies