Biotechnology and bioengineering – Page 3
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ResearchFirst direct chemical synthesis of a gene over 1700 nucleotides long
Innovative use of non-porous solid supports allows synthesis of very long oligonucleotides
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ResearchDesigner proteins to treat deadly snake bites could save thousands of lives
Small proteins can help to tackle some of the deadliest components of cobras and mambas
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ResearchCrispr gene-editing booster molecule can damage DNA far from target site
Researchers warn of unwanted side effects with genome editing chaperone
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ResearchIontronic gel droplets detect beating heart tissue
Microscale hydrogels converted into biocompatable electrical components
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ResearchTomato sweetness boosted by gene editing to knock out two genes
Glucose and fructose levels were increased by 30%
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NewsProtein design and structure prediction wins chemistry Nobel prize
David Baker, Demis Hassabis and John Jumper were rewarded for creating computational tools to design proteins and predict their structures that have ‘revolutionised biological chemistry’
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ResearchNanopore sequencing set to transform our understanding of proteins
Rapid sequencing technique can not only deal with proteins hundreds of amino acids long but can detect modifications
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ResearchYellow food dye could give doctors a new way to look beneath the skin
Tartrazine can safely and reversibly turn the skin of mice transparent
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ResearchTeaching enzymes new reactions through genetic code expansion and directed evolution
Anthony Green’s research group at the University of Manchester, UK, reengineers enzymes to have catalytic functions beyond those found in nature
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BusinessUS industry braced for change as election looms
Regulation, trade tariffs and innovation support top lists of concerns
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ArticleDriving innovation in the UK’s emerging biotechnology sector
Biotech startups and spinouts must overcome numerous challenges to get from lab to market. A new UK innovation hub aims to give this emerging sector the space, resources and expertise it needs.
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NewsAward-winning chemist threatens to sue critic
Tensions flare in latest dispute over spherical nucleic acid technology
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ResearchHybrid metabolism allows bacterium to get most out of fermentation and respiration
Engineered E. coli can turn unusable carbon sources into chemical feedstocks
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ResearchTherapeutic proteins can hitch a ride on parasite to bypass blood-brain barrier
Toxoplasma could be delivery agent for protein drugs – provided parasite can be made safe
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NewsAll clinical research using germline genome editing banned in China
New guidelines follow creation of first gene-edited babies three years ago by He Jiankui
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FeatureIs DNA the future of digital data storage?
DNA is being explored as a long-term solution to preserving digital information for future generations. Nina Notman reports
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ResearchNew gene-editing tool found in bacterium could carry out extensive genome remodelling
Highly selective mechanism can insert, remove and flip large portions of DNA
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ResearchGenetic engineering feat coaxes yeast to produce valuable vaccine compound
Yeast could head off supply fears for vaccines ingredient by replacing soapbark tree as source of adjuvant
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BusinessPan-cancer approval shows huge potential for antibody–drug conjugates
Enhertu gains approval based on gene expression rather than tumour location