Biotechnology and bioengineering – Page 5
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BusinessAn evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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NewsGenetically modified purple tomatoes receive US approval
Home growers will be able to purchase seeds from spring 2023
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ResearchYeast engineered to ferment sugars into chemotherapy drug precursors
Semisynthesis offers new route to anticancer drug vinblastine
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BusinessNature-inspired crop protection
Plant extracts, proteins and pheromones aiming to replace conventional chemical pesticides
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FeatureThe plant trade’s scientific secrets
Growers are using advanced techniques to mass-produce the next trendy houseplant. But Katrina Krämer finds that collectors’ demand for new varieties has also opened the door to deception and fraud
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ResearchCrispr editing of certain genes could trigger cell death
Researchers identify more than 3000 spots in the human genome where gene editing could cause toxic side effects and genomic instability
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ResearchRedox flow batteries charge up with peptide-based electrolytes
Study shows how electrolytes could be degraded using acid and heat
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FeatureCultured meat flexes its muscles
Rebecca Trager examines an emerging industry that is growing ‘meat’ outside of animals using cell lines cultivated in bioreactors
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OpinionWhy AlphaFold won’t revolutionise drug discovery
Protein structure prediction is a hard problem, but even harder ones remain
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ResearchRenewable rocket fuel made by genetically engineered soil bacteria
Bioengineered bacteria synthesise extremely energy dense cyclopropane chains
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OpinionAlzheimer’s, amyloid and abandoned antibodies
Biogen’s aducanumab is stumbling into obscurity. Where does that leave the amyloid hypothesis?
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ResearchEncapsulated bacteria show promise as injectable living drugs factories to treat diseases
Engineered E. coli produce insulin and vaccines in vivo
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ResearchLight-activated cancer treatment uses tumour-targeting enzymes to cut side effects
Enzymatic activation of a photosensitive prodrug in cancerous cells shows promise in mice
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ResearchBreaking bacteria’s genetic silence to synthesise antibiotics that evade resistance
Prospecting in bacterial genomes offers hope in search for new antimicrobial drugs
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ResearchGene therapy showcases technique to extend life in mice
Lab mice lived significantly longer after receiving one of two genes, delivered using a mouse herpes virus
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BusinessWhat is the future of Covid-19 pharmaceuticals?
Firms anticipate long-term markets for prevention and treatment
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ResearchCancer progression and harmful bacteria tracked with next-generation sequencing
Proof-of-principle study keeps an eye on leukaemia mutations and bacterial strains in patients
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FeatureThe incredible antibodies of sharks, llamas and camels
Sharks and llamas share a strange quirk of their immune systems. Hayley Bennett finds out how their ‘nanobodies’ could help us tackle Covid and a host of other diseases
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ResearchAI-engineered enzyme eats entire plastic containers
Enzyme with only five amino acid alterations depolymerises 51 different PET products faster and at lower temperature than other proteins
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ResearchYeast engineered to convert methanol into heparin
Production levels are currently low, but researchers hope the method could one day mean pharma doesn’t have to rely on animals for this essential medicine