Biotechnology and bioengineering – Page 4
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CareersCarving out a career as an amateur scientist
Lacking a degree has not stopped Sebastian Cocioba making waves in the world of biotechnology
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ResearchDiverse pharmaceutical building blocks prepared with evolved enzymes
Computation guides enzyme evolution to produce high-value drug compounds
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ResearchNMR spectroscopy used to guide evolution of better enzymes
Identifying mutagenic ‘hotspots’ could speed development of new proteins
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OpinionA promising breakthrough in liquid condensate compartmentalisation
Tears are RNA solvent droplets that could help engineer new functions into bacteria
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OpinionNobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
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BusinessAlzheimer’s antibody engenders anticipation
Tantalising press-released data on Biogen and Eisai’s lecanemab prompt questions without firm answers
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BusinessAn evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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NewsGenetically modified purple tomatoes receive US approval
Home growers will be able to purchase seeds from spring 2023
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ResearchYeast engineered to ferment sugars into chemotherapy drug precursors
Semisynthesis offers new route to anticancer drug vinblastine
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BusinessNature-inspired crop protection
Plant extracts, proteins and pheromones aiming to replace conventional chemical pesticides
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FeatureThe plant trade’s scientific secrets
Growers are using advanced techniques to mass-produce the next trendy houseplant. But Katrina Krämer finds that collectors’ demand for new varieties has also opened the door to deception and fraud
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ResearchCrispr editing of certain genes could trigger cell death
Researchers identify more than 3000 spots in the human genome where gene editing could cause toxic side effects and genomic instability
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ResearchRedox flow batteries charge up with peptide-based electrolytes
Study shows how electrolytes could be degraded using acid and heat
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FeatureCultured meat flexes its muscles
Rebecca Trager examines an emerging industry that is growing ‘meat’ outside of animals using cell lines cultivated in bioreactors
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OpinionWhy AlphaFold won’t revolutionise drug discovery
Protein structure prediction is a hard problem, but even harder ones remain
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ResearchRenewable rocket fuel made by genetically engineered soil bacteria
Bioengineered bacteria synthesise extremely energy dense cyclopropane chains
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OpinionAlzheimer’s, amyloid and abandoned antibodies
Biogen’s aducanumab is stumbling into obscurity. Where does that leave the amyloid hypothesis?
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ResearchEncapsulated bacteria show promise as injectable living drugs factories to treat diseases
Engineered E. coli produce insulin and vaccines in vivo
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ResearchLight-activated cancer treatment uses tumour-targeting enzymes to cut side effects
Enzymatic activation of a photosensitive prodrug in cancerous cells shows promise in mice
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ResearchBreaking bacteria’s genetic silence to synthesise antibiotics that evade resistance
Prospecting in bacterial genomes offers hope in search for new antimicrobial drugs