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ResearchFlow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
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News
Swipe right to help in the fight against Huntington’s disease
Citizen science project improves understanding of protein misfolding disorders like Huntington’s and Alzheimer’s diseases
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Feature
Separating turmeric fact from fiction
Thousands of papers have been published on curcumin’s healing potential, but its usefulness is not yet proven, finds Andy Extance
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Research
Ammonium bicarbonate trick enables sophisticated lipid analysis
Tandem mass spectrometry method can distinguish lipid isomers
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News
Study claiming gene-edited babies were more likely to die young was wrong
Database bias introduced major error in a now retracted study on Crispr babies’ mortality
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Business
The rise of venture philanthropy
More and more charities are investing in companies, and looking for returns on that investment, as an alternative to traditional grants
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Business
Nitrosamine contamination withdrawals spread to new drugs
After ranitidine recalls, EU regulators instruct companies to review all their products for potential impurities
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Research
Alzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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Business
Sixth in a line of Alzheimer’s drugs fails in trials
Treatments designed to stop amyloid peptide formation all seem to cause cognitive impairment rather than prevent it
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Opinion
Under a cloud
Chemical detective work is needed to track down what’s been killing e-cigarette users
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Research
Elusive protein and key to many tropical diseases found after decades of searching
Discovery offers powerful new target to treat trypanosome parasite illnesses that affect millions
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Podcast
Sodium fluoroacetate
The controversial killer compound – also known as 1080 – being used to protect New Zealand’s native wildlife
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News
US children’s hospital takes delivery of one of world’s most powerful NMR spectrometers
Instrument offers unprecedented opportunities to study disease development
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News
Deaths from vaping-linked lung disease in US connected to vitamin E additive
Tocopheryl acetate implicated in 380 cases of severe lung disease and six deaths
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Review
Mescaline: A Global History of the First Psychedelic
A story about the people who harvested, used, abused, regulated and investigated the mind-altering drug
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Research
Glucose derivative replaces BPA in sustainable polycarbonate plastic
Transparent engineered plastic ditches hormone disruptor and lung irritant
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Business
Aquaffirm’s enzymatic arsenic sensors
Cheap, disposable electrochemistry test strips help communities steer clear of contaminated wells
