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FeatureThe name’s bond, chemical bond
Kathryn Harkup explores the poisons – real and fictional – used in Bond films
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Business
Fully synthetic proteins make tailored medicines
Bright Peak Therapeutics makes modified protein drugs from scratch
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Business
The future of ‘next generation’ DNA sequencing
As it gets cheaper and easier to read genetic code, its applications are expanding rapidly
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Article
The lifesaving work of Evelyn Hickmans
Anne Green tells us how a female chemist almost single-handedly established paediatric clinical chemistry and led to a first in global health
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Business
US judge accepts Purdue’s opioid bankruptcy settlement plan
Deal releases $4.3bn to combat addiction, but protects Sackler family from litigation
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News
US intelligence can’t agree if Covid-19 came from an animal or a lab
After months of investigation agencies remain divided on most likely origin of Sars-CoV-2
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Business
US bans chlorpyrifos on all food crops
Environmental agency removes remaining exceptions for agricultural use of controversial insecticide
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Business
The multi-pronged search for Covid-19 treatments
Drugs that block infection or reduce inflammation will complement vaccine protection
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Business
Budget cuts at UK medicines regulator raise eyebrows
MHRA to cut 300 jobs amid financial pressures arising from Brexit
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News
Research and regulations face-up to a new era of non-animal testing alternatives
Hopes raised that approval for skin sensitisation test could mark the start of a raft of in vitro toxicity tests
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Research
Neural network scours vast chemical space to design drug-delivering peptides
Oligonucleotide drug activity boosted 50-fold with peptide designed by machine learning algorithm
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Business
Developing countries sidelined in Covid-19 vaccine scramble
Lack of funds and local manufacturing capacity has prevented Covax from competing with wealthier nations’ self-interest
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Feature
How the power of smell could identify new medical tests
Diagnosis by odour is nothing to be sniffed at, finds Ian Le Guillou
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Business
Pfizer backs protein degrader drugs with Arvinas deal
$1bn investment to commercialise breast cancer treatment
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Research
Snake extract used to speed up haemostasis in new bioadhesive
Hydrogel-based bioadhesive could be suitable for arterial injuries
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Business
Non-animal test for skin sensitisation gets OECD approval
Combination strategy developed by BASF and Givaudan is the first complete replacement for animal testing
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Research
Electrochemical DNA on a chip sensor detects bacterial urinary tract infections faster
Synthetic nucleic acid probes combine with tiny star-shaped electrodes tests for bacteria in less than an hour
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Business
Sartan contaminant recall hits generics manufacturers
Three European suppliers recalling multiple batches of medicines owing to active ingredient contamination
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News
Race to understand Sars-CoV-2 variants amid fears virus might evade vaccines
Biochemical basis behind coronavirus variants’ success could hold key to defeating them
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Business
Regeneron’s Covid-19 antibodies help those who can’t make their own
Regn-Cov2 reduces deaths and shortens hospitalisation for these patients, even when given at late stages of infection
