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OpinionAlzheimer’s, amyloid and abandoned antibodies
Biogen’s aducanumab is stumbling into obscurity. Where does that leave the amyloid hypothesis?
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News
New questions raised over Sputnik Covid vaccine results point to fraudulent practices
Analysis comparing Sputnik results with five other Covid vaccines finds phase 3 trial outcome is highly improbable
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Research
Encapsulated bacteria show promise as injectable living drugs factories to treat diseases
Engineered E. coli produce insulin and vaccines in vivo
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Feature
Using genetics to personalise prescriptions
We’ve known for a long time that different people respond to certain drugs to very different extents, but now cheap DNA testing could make these disparities a thing of the past, as Ian Le Guillou reports
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Business
Data reveals disparities in US refinery benzene emissions
Monitoring shows several facilities consistently exceed federal action levels
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Research
Gene therapy showcases technique to extend life in mice
Lab mice lived significantly longer after receiving one of two genes, delivered using a mouse herpes virus
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Research
Gut microbiome analysis spots sleep-deprived mice
Fluorescence-based sensing array that identifies bacteria in stool samples could be developed into a tool for diagnosing various conditions
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Research
These 15 molecules trigger Covid smell disorder
Researchers identify compounds that trigger parosmia, the condition that makes coffee smell like burning rubbish
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Feature
3D printing adds another dimension
Nina Notman learns how 4D printing is opening the door to unique smart materials whose applications may only be limited by our imaginations
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Research
Cancer progression and harmful bacteria tracked with next-generation sequencing
Proof-of-principle study keeps an eye on leukaemia mutations and bacterial strains in patients
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Feature
The incredible antibodies of sharks, llamas and camels
Sharks and llamas share a strange quirk of their immune systems. Hayley Bennett finds out how their ‘nanobodies’ could help us tackle Covid and a host of other diseases
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Opinion
Wastewater has huge potential for global health
Monitoring programmes can help healthcare and empower communities
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Feature
The human health observatory in our sewers
From tracking disease outbreaks to monitoring drug use, there’s a lot to be learned from the things we flush down the toilet, Katrina Krämer finds
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Opinion
Letters: May 2022
Readers reminisce about a smelly interview question and curl up with their favourite arrow-based textbook
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Business
UK takes subscription approach for new antibiotics
Decoupling payment from prescriptions helps preserve last-line antibiotics and encourage R&D
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Research
Discovery of microplastics in people raises difficult questions about health implications
Scientists keep finding tiny polymer particles in lungs, blood and placentas – but what does that mean means for people’s health?
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News
Chemistry Nobel laureate Sidney Altman dies at 82
Canadian–American molecular biologist won the 1989 prize for discovering RNA’s catalytic ability
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Sponsored
Nanotechnology for a healthier, cleaner world for all
Using novel polymer fluorophores to study, detect and treat life-threatening diseases
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Business
Patent office cements priority for Crispr gene editing in cells
Nobel laureates’ failed challenge means companies may need extra patent licenses
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Research
Array of compounds found in plastics promote fat cell formation in vitro
A third of thousands of chemicals that leach from consumer polymers linked to the development of fat cells
