All oligonucleotide drug articles
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Research
Biocatalytic process shows promise for large-scale medicinal oligonucleotide production
Promising nucleic acid therapies could be made more cheaply, greenly and simply
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Research
Method to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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Research
Neural network scours vast chemical space to design drug-delivering peptides
Oligonucleotide drug activity boosted 50-fold with peptide designed by machine learning algorithm
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Business
FDA’s first Duchenne drug approval reveals schism
Oligonucleotide drug reaches market amid pressure from patient families and strife over ‘patient-focused drug development’ at the regulator
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Feature
Oligonucleotide drugs step up
Structural innovations are overcoming oligonucleotide drugs’ historical flaws, discovers Andy Extance
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Research
Ahmed Elmouna: Oligos in the desert
Ahmed Elmouna talks to Jennifer Newton about the ups and downs of setting up a new research unit