Organic chemistry – Page 58
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FeatureOrganic pioneer
Christopher Ingold's insights into mechanism and reactivity established many of the principles of organic chemistry. John Ridd reveals more about his life and work
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Opinion
Rubioncolin B
Researchers have successfully synthesised the complex natural product Rubioncolin B using a biomimetic approach that mimics nature's own chemistry, providing new insights into how plants construct these intricate molecules.
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Opinion
Hypocrellin A
Marisa Kozlowski's team at the University of Pennsylvania has developed an elegant synthesis of hypocrellin A that uses helical chirality to control traditional stereocentres through a dynamic stereochemistry transfer reaction.
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Opinion
Callipeltoside A
Harvard's David Evans has applied his renowned aldol reaction expertise to synthesise callipeltoside A, a complex natural product that has challenged chemists since its isolation in 1996.
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Opinion
Fashion drives natural product synthesis target selection
Total synthesis is not immune to the vagaries of fickle fashion, says Dylan Stiles
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Opinion
Superacids: the strongest chemicals that can protonate anything
What could possibly contain the strongest acid in the world, asks Dylan Stiles
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FeatureAt the top of the cascade
David MacMillan, a leading light in organocatalysis, takes James Mitchell Crow on a tour of the field
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Opinion
Buckminsterfullerene and the quest for funny-looking molecules
Dylan Stiles just loves those funny-looking molecules
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FeatureThe click concept
To some, 'click chemistry' is simply a relabelling of standard organic chemistry practices. Others follow its principles almost religiously
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OpinionWhy synthetic organic chemistry is the ultimate creative process
Dylan Stiles explains why he loves to go skydiving in a lab coat
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FeatureThree share prize for metathesis work
The discoveries made by this year's Nobel laureates have had a great impact on new drug developments, polymeric materials and industrial syntheses. Karen Harries-Rees reports.