Pharmaceutical industry – Page 4
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FeatureBypassing the blood–brain barrier
Researchers are on a quest to outsmart and overcome the sophisticated security system of the brain. Julia Robinson reports on some of the approaches being studied
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OpinionThe US abortion drugs regulation challenge has stalled, but it will return
Having failed in the US Supreme Court, anti-abortion activists are trying other ways to prevent access to mifepristone
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FeatureSparking industry’s interest in electrosynthesis
Using electrons instead of reagents offers many potential benefits, but there are still barriers to overcome, as Rachel Brazil reports
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BusinessModerna’s mRNA vaccine approved for RSV
US approval adds complementary option to protein-based vaccines for respiratory syncytial virus
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OpinionWill science ever reach an end?
While the rate of discoveries in any field may slow over time, the frontier creeps ever further
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ResearchSimplified hydroformylation replaces rhodium with base metal
Bench-friendly asymmetric hydroformylation swaps toxic gas and expensive catalyst for cheap reagents and mild conditions
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BusinessPan-cancer approval shows huge potential for antibody–drug conjugates
Enhertu gains approval based on gene expression rather than tumour location
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ResearchHow HIV drugs have changed over the decades
From one big pill that only prolonged lives a few months, through the 20 pills a day years to modern combination therapies, treating HIV is a science success story
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OpinionLab automation gives me more time at the top of the mountain
Getting back to the bench reminds Derek Lowe how much has changed in 40 years
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ResearchScreening reveals thousands of ‘undrugged, yet druggable’ proteins
Collaboration involving Pfizer develops freely accessible AI tool to probe protein–compound interactions
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ResearchCould mechanochemistry have saved Abbott Laboratories $250 million?
Ball milling solves problem of disappearing ritonavir polymorph
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BusinessSix dead in explosion and fire at Indian pharmaceutical plant
At least 17 others injured at SB Organics facility near Hyderabad
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OpinionWater isn’t normal
Despite its familiarity, water is a chemical oddity. But that’s what makes it fascinating
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BusinessUS government moves to block Chinese biotechs’ operations
WuXi Apptec and others accused of national security risk, as trade groups back legislation limiting their activities
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OpinionFrom one sinking ship to another?
Biogen abandoning Alzheimer’s antibody aducanumab is unusual, but hardly surprising, says Derek Lowe
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OpinionMaking chemicals safe and sustainable
The green transition is an opportunity to also make industry simpler and safer
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BusinessBig deals confirm renewed interest in radiopharmaceuticals
Acquisitions of RayzeBio and Point Biopharma highlight the potential of targeting radioactivity directly to tumour cells
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BusinessNovo Holdings to buy contract manufacturer Catalent for $16.5 billion
Parent firm will then sell on three manufacturing sites to Novo Nordisk to boost capacity for diabetes and weight loss drugs
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BusinessUS industry leaders repeat calls to reinstate security programme
Six month gap in vetting people with access to high-risk chemicals means potential threats may have been missed