Pharmaceutical industry – Page 4
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FeatureThe GLP-1 weight loss revolution
Glucagon-like peptide-1 agonist drugs, such as semaglutide, could save countless lives at risk due to diabetes and obesity. Rachel Brazil looks at the difficulties in making the peptides themselves, and what’s coming next
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Business17 dead in solvent explosion at Indian plant
Dozens more injured at pharmaceutical ingredients manufacturer in Andhra Pradesh
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BusinessMDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
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WebinarAI meets chemistry: Standigm’s breakthrough with Synthia Retrosynthesis Software
Discover how Standigm’s use of Synthia can accelerate AI-driven drug discovery
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OpinionMedicinal chemistry’s biological blind spots
Despite advances in modern medicine, there are some big gaps in our knowledge
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BusinessExplainer: Why drug shortages happen and how can we reduce them?
Record-high numbers of drugs are in short supply, from chemotherapy and antibiotics to hormone replacements
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OpinionWorking in the chemical industries, plural
Despite often being presented as a monolith, there’s a huge variety of activities, working practices and reaction scales across industrial research
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ResearchTherapeutic proteins can hitch a ride on parasite to bypass blood-brain barrier
Toxoplasma could be delivery agent for protein drugs – provided parasite can be made safe
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BusinessWeight-loss drugmakers bet billions on boosting supplies
Eli Lilly and Novo Nordisk invest to expand in-house manufacturing of GLP-1 drugs
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ResearchDrugs and vaccines could be freed from cold chains by hydrogel
Stiff gel prevents proteins from aggregating, preserving their therapeutic power
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BusinessRed Sea attacks are reshaping chemical supply chains
High demand and reduced capacity have kept freight prices high
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BusinessExplainer: How is the US pharmaceutical patent system being misused?
What are ‘evergreening’ and ‘thicketing’ and what is being done to reform the system and aid competition?
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BusinessUS Supreme Court quashes Purdue opioid bankruptcy plan
Ruling says deal cannot grant Sackler family owners protection from prosecution
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ResearchCompanion compound for naloxone could boost opioid reversal effects, save lives
Discovery could help in fight against super-strength opioids such as fentanyl
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FeatureBypassing the blood–brain barrier
Researchers are on a quest to outsmart and overcome the sophisticated security system of the brain. Julia Robinson reports on some of the approaches being studied
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OpinionThe US abortion drugs regulation challenge has stalled, but it will return
Having failed in the US Supreme Court, anti-abortion activists are trying other ways to prevent access to mifepristone
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FeatureSparking industry’s interest in electrosynthesis
Using electrons instead of reagents offers many potential benefits, but there are still barriers to overcome, as Rachel Brazil reports
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BusinessModerna’s mRNA vaccine approved for RSV
US approval adds complementary option to protein-based vaccines for respiratory syncytial virus
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OpinionWill science ever reach an end?
While the rate of discoveries in any field may slow over time, the frontier creeps ever further