Biochemistry
The latest chemistry news and research on biochemistry, including proteomics, metabolism, enzymes and nucleic acid chemistry, from the Royal Society of Chemistry's magazine, Chemistry World
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OpinionProteins’ shape and function are two sides of the same coin
A new perspective on the relationship between chemistry and biology
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ResearchAnalytical chemistry tools point to the future of personalised medical diagnostics
Molecular fingerprinting techniques outperform standard blood tests for detecting the onset of many diseases
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ResearchHybrid metabolism allows bacterium to get most out of fermentation and respiration
Engineered E. coli can turn unusable carbon sources into chemical feedstocks
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NewsExplainer: Why athletes are taking sodium bicarbonate supplements
Why runners are taking pills containing a common kitchen ingredient
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OpinionMedicinal chemistry’s biological blind spots
Despite advances in modern medicine, there are some big gaps in our knowledge
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OpinionUnderstanding our brains is complicated, beware of simple ideas
Stepping up from chemistry to complexity
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FeatureBrain chemistry basics
Andy Extance looks into the latest in Alzheimer’s disease, pain and memory
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FeatureBypassing the blood–brain barrier
Researchers are on a quest to outsmart and overcome the sophisticated security system of the brain. Julia Robinson reports on some of the approaches being studied
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FeatureWhy don’t we know how antidepressants work yet?
Selective serotonin reuptake inhibitors are at the centre of a collision between social and biochemical outlooks on depression, finds Andy Extance
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FeatureThe proteins that drive drug addiction
Jamie Durrani speaks to researchers exploring how epigenetic changes in the brain affect drug-seeking behaviours
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ResearchNew mechanism identified that is potentially linked to very early stages of Alzheimer’s
Understanding role of fragments of amyloid protein could lead to novel therapies for the disease
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ResearchMicroscopy structures reveal mechanism behind bitter taste
Cryo-EM images provide a detailed picture of bitter taste receptors
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FeatureHow microbes influence our brain health
Our gut microbiome has been linked to conditions such as Parkinson’s and Alzheimer’s. Anthony King reports on the connections
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ResearchDeep learning algorithm predicts structures of biomolecular assemblies
RoseTTAFold extended to predict structures of proteins bound to small molecules
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ResearchEnzyme engineering makes blue denim greener
Environmentally friendlier alternative to indigo dye can now be made at a competitive price
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FeatureSmall molecules that switch up cell development could transform medicine
Turning mature somatic cells back into flexible stem cells using small molecules could revolutionise medicine, especially for regeneration and cancer. Philip Ball reports
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FeatureThe chemistry of love
There’s chemistry behind every step of a romantic relationship, from the initial spark to the pain of break up, as Zahra Khan discovers
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FeatureMore than a mirror-image: left-handed nucleic acids
Now a biological reality, researchers are starting to figure out the many roles of left-handed nucleic acids such as Z-DNA – from immunity to controlling our genetics. Rachel Brazil reports
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ResearchHeavy metals are potential ovarian toxicants
Exposure to metals like arsenic, cadmium and mercury linked to reduced egg production, earlier menopause for middle-aged women