AI takes step towards cracking biology’s toughest problem – protein sequencing
By 
Victoria Corless2025-03-31T13:30:00
The team hopes the system will eventually be as influential as AlphaFold was for protein structure prediction
A new AI system, dubbed InstaNovo, could revolutionise protein sequencing just as AlphaFold transformed protein structure prediction, its developers claim.
While DNA sequencing is routine, determining protein sequences remains one of biology’s toughest challenges, says corresponding author Timothy Jenkins of the Technical University of Denmark. InstaNovo aims to change that by directly reading protein sequences from raw experimental data, unlocking vast areas of previously inaccessible biology.