Biochemistry – Page 3
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FeatureThe science behind a ‘runner’s high’
Exercise addicts need to stop talking about getting their endorphin hit, writes Hayley Bennett, and start looking at endocannabinoids
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ResearchMolecular fossils solve evolutionary mystery
Fossilised protosteroids confirm Nobel-prizewinner’s decades-old prediction
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ResearchAncient microbial natural products reconstructed from Neanderthal dental plaques
Palaeogenomic approach allows natural product researchers to ‘go back in time’
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FeatureA new generation of materials inspired by teeth
Ian Le Guillou finds that some of nature’s toughest structures are helping scientists to develop new fibres that could revolutionise fabrics
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ResearchOrange climbers make fluorescent blue molecules
Naturally occurring aggregation-induced emission luminogens could find use in biomedical imaging
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NewsThe launch of a new field: precision microbiome editing
Nobel laureate Jennifer Doudna is helping lead a new $70 million project combining metagenomics and CRISPR to solve health, climate problems
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ResearchNMR reveals sialic acid biosynthesis in real time
Using NMR, scientists can directly measure sialic acid enzyme conversion velocities for the first time
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ResearchWired-up symbiotic multi-organism can turn sunlight and air into valuable proteins
Symbiont could enable microfactories to produce biochemicals for food, farming and drugs
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ResearchSoapbark tree’s biosynthetic pathway for vaccine adjuvant saponins
Researchers use genome mining and bioengineering techniques to map out route
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FeatureHow do plants sense stress?
How does an organism without a brain or a nervous system sense when it’s under attack? Hayley Bennett presents the plant world’s strange yet sophisticated system for responding to wounding
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ResearchA safer, coral-friendly sunscreen is on the horizon
Polymeric UV filter doesn’t harm algae, coral or mice in tests
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FeatureChanging the game in protein structure prediction
Have AlphaFold and other machine learning techniques essentially solved the formerly fiendish problem, or is there still more to be done? Clare Sansom reports
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NewsNobel laureate and recombinant DNA pioneer Paul Berg dies
Winner of the 1980 chemistry Nobel prize has passed away in his home on Stanford’s campus at 96
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ResearchLipophilicity helps explain psychedelic drugs’ therapeutic effects
Understanding why psychedelic drugs that bind to serotonin receptors promote neuron growth, while serotonin itself does not
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ResearchOyster mushroom unleashes chemical warfare on its nematode prey
Fungus discovered to be using 3-octanone to paralyse and kill worms
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FeatureOmega-3s and brain health
Modern diets can leave us short on essential fatty acids. Barbara Pinho looks into how this is affecting our health and our brains in particular
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ResearchSurprise discovery as clam found to be producing complex antibiotic
Erythromycin was previously believed to be only synthesised by bacteria
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FeatureCelebrating Louis Pasteur’s bicentenary
Mike Sutton reflects on the dramatic discoveries of Louis Pasteur, born 200 years ago
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OpinionMartin Chalfie: ‘I decided I wasn’t going to be a scientist’
The Nobel prizewinner on breaking a promise to himself and the test he had to pass to receive his medal
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FeatureHow click conquered chemistry
Katrina Krämer tells the story of how click and bioorthogonal chemistry came to win the 2022 Nobel prize