Biochemistry – Page 10
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ResearchFirst Crispr cancer trial in humans shows safety and durability
Immune-cell modifications target tumours and lift the PD-1 ‘brake’
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PodcastVitamin B12 or Cobalamin
If you’re trying out a vegan diet, you’re likely to be told to make sure you get enough vitamin B12. But what is B12, where do we get it from, and how can we be sure we’re getting enough?
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Feature
Can chemists crack our cells’ sugar code?
Rachel Brazil talks to the scientists trying to understand the sweet mystery of the glycome
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ResearchBlood test picks out proteins that accurately predict age
Discovery could lead to better preventive medicine
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PodcastIminosugars
After some promising results treating ill pets, some researchers think iminosugars could become treatments for infection and even cancer. Mike Freemantle explores the buzz around iminohoney
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ResearchMystery of why magic mushrooms go blue solved
Chemists reveal colourful indigo-like polymers that turn psychotropic mushrooms blue when cut
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PodcastTryptophan
Ben Valsler tackles ‘zombie facts’ and the tenuous connection between tryptophan in turkey and your post-Thanksgiving dinner doze
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ResearchRobotic system can plan and perform biosynthesis without human intervention
New strategy combines machine learning with automation and has proven itself optimising a complex biochemical pathway
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PodcastHypoxia-inducible factors – HIFs
The oxygen sensors that help life react to changing conditions, key to the 2019 Nobel prize in physiology or medicine
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ResearchSynthetic flame retardant compounds turn up as marine natural products
Finding an alga that biosynthesises halogenated anilines increases likelihood of finding an organism that can degrade the toxic compounds too
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ResearchWhy photosynthetic organisms evolved to have dimeric reaction centres
Excitation energy transfer enhancements thought to compensate for decrease in charge transfer efficiency of going from monomers to dimers
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ResearchResurrected enzyme aces cellulose catalysis
Protein that survived extreme conditions on early Earth could be a boon for biofuel industry
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WebinarMiniaturise the haystack: DNA-Encoded Libraries for drug discovery
A DNA-Encoded Library (DEL) case study and fragment-based DEL discovery insight from DyNAbind
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OpinionThe crowdsourced analysis hoping to go viral
Crowdsourcing image analysis to better understand how viruses multiply inside cells
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NewsDarpa wants to genetically engineer soldiers’ skin bacteria to protect them from mosquitoes
Pentagon programme aims to change chemical cues released by human skin microbes to provide a long-term defence from mosquito-borne diseases
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ResearchEnzyme evolved to selectively functionalise carbon–hydrogen bonds
Lactam libraries created by engineered bacterial enzyme offer new way to fight antibiotic resistance
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ResearchFirst bacterium with a totally redesigned genome created
Designer E. coli uses a simplified genetic code to make proteins
