‘Hidden grammar’ explains proteins’ distribution into sub-cellular condensates
By 
Philip Ball2025-02-11T09:30:00
Proteins’ amino-acid sequences appear to guide their access to blob-like aggregates involved in many cell processes
Proteins are generally considered to be programmed with a folding code: the sequence of amino acids along their chains determines how they fold into compact, functional shapes. Researchers in the US have now proposed that proteins also carry a second code, which acts as a kind of address label directing them towards cell compartments called biomolecular condensates.1