Biochemistry – Page 8
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ResearchRobotic system can plan and perform biosynthesis without human intervention
New strategy combines machine learning with automation and has proven itself optimising a complex biochemical pathway
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PodcastHypoxia-inducible factors – HIFs
The oxygen sensors that help life react to changing conditions, key to the 2019 Nobel prize in physiology or medicine
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ResearchSynthetic flame retardant compounds turn up as marine natural products
Finding an alga that biosynthesises halogenated anilines increases likelihood of finding an organism that can degrade the toxic compounds too
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ResearchWhy photosynthetic organisms evolved to have dimeric reaction centres
Excitation energy transfer enhancements thought to compensate for decrease in charge transfer efficiency of going from monomers to dimers
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ResearchResurrected enzyme aces cellulose catalysis
Protein that survived extreme conditions on early Earth could be a boon for biofuel industry
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WebinarMiniaturise the haystack: DNA-Encoded Libraries for drug discovery
A DNA-Encoded Library (DEL) case study and fragment-based DEL discovery insight from DyNAbind
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OpinionThe crowdsourced analysis hoping to go viral
Crowdsourcing image analysis to better understand how viruses multiply inside cells
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NewsDarpa wants to genetically engineer soldiers’ skin bacteria to protect them from mosquitoes
Pentagon programme aims to change chemical cues released by human skin microbes to provide a long-term defence from mosquito-borne diseases
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ResearchEnzyme evolved to selectively functionalise carbon–hydrogen bonds
Lactam libraries created by engineered bacterial enzyme offer new way to fight antibiotic resistance
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ResearchFirst bacterium with a totally redesigned genome created
Designer E. coli uses a simplified genetic code to make proteins
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ResearchCrispr gene-editor helps find new treatments for box jellyfish venom
Cyclodextrins show promise treating stings
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ResearchSwitching to sulfur stops deadly bacteria growth
Modified sugar prevents growth of Clostridium difficile while retaining useful properties
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PodcastLimulus Amebocyte Lysate
Frances Addison takes a look at the discovery that brought horseshoe crabs to the heart of the pharmaceutical industry
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PodcastLevothyroxine
Kit Chapman investigates the drug that has been one of the top five prescription medications in the UK every year for the last two decades
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ResearchRadical route produces non-natural polymers inside cells
Strategy could enable scientists to manipulate, track and control cellular behaviour by generating macromolecules within cells
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ResearchTranscription controlled by non-natural DNA modifications
Proof-of-concept for artificial chemical epigenetics