Biochemistry – Page 4
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FeatureSequencing one cell at a time
New advances that allow scientists to uncover the molecular differences between individual cells could revolutionise medicine, Ian le Guillou finds
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ResearchBiochemical secrets of tarantula’s painful bite could point to perfect painkillers
King baboon spider venom could help scientists develop potent analgesics
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OpinionThe shadow of drug resistance
Why do some medicines stop working, and can we avoid it for Covid-19 antivirals?
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ResearchEngineered enzyme speeds up sedate organic reaction
Biochemical optimisation applied to the Morita–Hillman–Baylis reaction
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ResearchEvolved enzymes carry out new-to-nature radical chemistry
Directed evolution produces enzymes that can ‘tame’ radical intermediates for asymmetric catalytic reactions
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ResearchSingle-celled marine organism first to be found releasing oxygen in the dark
Discovery of new biological pathway in widespread archaea could transform understanding of oceans’ fertility
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ResearchHeavy oil-eating microbe grown in lab for the first time
Archaeon that breaks down long alkanes into methane and carbon dioxide could be used for energy recovery from depleted oil reservoirs
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OpinionJune Lindsey, another forgotten woman in the story of DNA
Her discovery of adenine and guanine’s structure was a key part of solving the DNA double helix puzzle – yet her contributions are almost forgotten
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OpinionHooray for milk
We’re still uncovering the secrets of breast milk, but what we know so far is fascinating
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ResearchFirst carbon-making microbes discovered
Mysterious black material produced by deep sea archaea and bacteria found to be carbon
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ResearchPossible dinosaur DNA discovered in 125-million-year-old fossil
But that doesn’t mean we can clone extinct species Jurassic Park-style
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ResearchTiny shear forces have big effect on protein reactions
Proteins react faster under the forces they experience when they squeeze through blood vessels
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ResearchDNA robot controls live cells’ movement
Molecular machine walks across cell membrane to activate cellular migration
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FeatureHow a virus ancestor powers our memory’s chemistry
Andy Extance tells the astonishing story of the Arc protein and its capsid forms, and the questions it poses
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ResearchMirror image enzyme constructs longest ever mirror DNA strand
Since chirally inverted DNA is more stable than its natural counterpart, it can be used to encode secret messages
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ResearchEnigmatic DNA dubbed ‘Borgs’ discovered in methane-metabolising microbes
The large nucleic acid structures may help bacteria play a role in regulating global methane
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ResearchSnake extract used to speed up haemostasis in new bioadhesive
Hydrogel-based bioadhesive could be suitable for arterial injuries
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ResearchIndividual cell’s energy metabolism caught on camera for the first time
Combining machine learning with fluorescence imaging provides new insight in glycolysis and might help with development of new therapies for cancer
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OpinionOpening up a cellular black box
Working out how biomolecular condensates work may reveal a lot about the success or failure of different drugs
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ResearchProtein-shaped sweets help students understand complex molecular structures
Edible protein models that can be identified by mouth could make chemistry education more inclusive to blind and visually impaired students