All DNA articles
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BusinessEpigenetic editors enter clinical trials
New wave of precision medicines amplify or silence genes, without altering genetic code
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FeatureThe circles of DNA that cause cancer
Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their secrets
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ResearchAI inspired by AlphaFold can predict chromatin structures found in chromosomes
System could help unravel how genome folding influences genes
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ResearchComputer simulation of carbonless DNA prompt researchers to consider alternative biochemistries
Researchers swap nitrogen and boron into DNA to create analogues that are geometrically and electrostatically equivalent to conventional DNA
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OpinionThere are no life lessons to be learned in AI’s Chinese Room
There’s a lot more lab work to do before we understand the ‘language of life’
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OpinionLetters: August 2024
Readers share their connections to the Flixborough disaster, discuss the importance of inorganic neurochemistry and more
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FeatureIs DNA the future of digital data storage?
DNA is being explored as a long-term solution to preserving digital information for future generations. Nina Notman reports
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OpinionLetters: June 2024
Readers find answers in industry, celebrate Eiji Osawa and continue the Z-DNA debate
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FeatureMore than a mirror-image: left-handed nucleic acids
Now a biological reality, researchers are starting to figure out the many roles of left-handed nucleic acids such as Z-DNA – from immunity to controlling our genetics. Rachel Brazil reports
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OpinionAn unprecedented supramolecular structure brings new complexities to life
The transcription factor FOXP3’s interactions with DNA present more evidence of the importance of disorder
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FeatureUsing DNA evidence to picture suspects
Forensic DNA phenotyping predicts people’s appearance and reveals their ancestry, finds Andy Extance, but has some significant challenges to overcome
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NewsOverlooked documents shed new light on double helix discovery
Rosalind Franklin was more than just a ‘wronged heroine’
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ResearchPeptide tags that encode chemical libraries could revolutionise drug discovery
Simple strings of amino acids store over 4 gigabits of data, offering a highly stable solution for screening small molecule libraries
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NewsNobel laureate and recombinant DNA pioneer Paul Berg dies
Winner of the 1980 chemistry Nobel prize has passed away in his home on Stanford’s campus at 96
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ResearchArtificially expanded genetic alphabet evolves enzymes for the first time
Libraries of short DNA sequences incorporating synthetic nucleotides perform better as enzymes than ordinary DNA
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OpinionCracking codons
Understanding how chemistry links RNA triplets to the properties of amino acids
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FeatureHow a murder and a bombing cleaned up DNA profiling
The UK pioneered a forensic process to identify suspects from tiny amounts of DNA, but occasional flaws had big consequences. Andy Extance pieces together the whole story for the first time
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OpinionJacqueline Barton: ‘I want to focus on the good stuff’
The Caltech chemist talks about her life as a New Yorker and female scientific powerhouse
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ResearchAll of life’s nucleic acids could have extraterrestrial origins
All five nucleobases of RNA and DNA found in three meteorites
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NewsChemistry Nobel laureate Sidney Altman dies at 82
Canadian–American molecular biologist won the 1989 prize for discovering RNA’s catalytic ability