Drug discovery and development – Page 6
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News
Drug discovery AI that developed new nerve agents raises difficult questions
Researchers shocked by how easily algorithm discovered novel poisons even deadlier than VX
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Opinion
A spanner in the works
Most drugs work by breaking or stopping something, rather than by making something faster or better
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Business
Moderna sued over Covid-19 vaccine-related patents
Arbutus and Genevant say lipid nanoparticles that protect mRNA infringe six key patents
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Business
Trials start of mRNA vaccine for HIV
First steps towards protection from the many and variable viral strains
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Research
Left-handed nanoparticles are far better vaccine adjuvants than their mirror images
Chiral gold nanoparticles shown for the first time to elicit differing immune responses in cells and live mice
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News
Explainer: How do the Covid vaccines measure up against each other and omicron?
Looking at how the evidence stacks up for vaccines against variants and how their performance holds up over time
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Opinion
Letters: February 2022
Readers investigate June Lindsey’s legacy, question policy and celebrate vaccination
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Opinion
The shadow of drug resistance
Why do some medicines stop working, and can we avoid it for Covid-19 antivirals?
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Opinion
The law of conservation of data
AI and machine learning are useful and powerful, but they need high quality data inputs that aren’t available yet for drug discovery
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Opinion
When regulatory cooperation goes too far, we all lose
Were FDA staff unduly influenced by Biogen in approving Alzheimer’s antibody?
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Business
Pharmaceuticals roundup 2021
It’s been another dramatic, pandemic-dominated year for the pharmaceutical industry
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Webinar
Using flow chemistry to give early drug discovery processes a boost
Discover how pioneering modular flow chemistry technologies can unlock the potential for discovery chemists to accelerate research
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Business
Pfizer sues former employee for alleged trade secret theft
Chun Xiao Li downloaded thousands of confidential documents before resigning
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Business
Covid-19 antivirals surge forward
Promising results from Pfizer trial, while UK approves Merck & Co’s molnupiravir
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Research
Gallium helps sneak antibiotic payload into bacterial cells
Compound is more potent than parent drug ciprofloxacin against Staphylococcus aureus
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Feature
mRNA vaccines for Covid and beyond
Already hailed as a miracle, the new vaccine technology could protect us from other diseases, Clare Sansom finds
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Article
Facilitating the future
A view from the top at Johnson Matthey on the future of drug development
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Opinion
A vaccine for all seasons?
Phase 1 clinical trials have begun on a candidate that could work against a wide range of flu viruses
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News
First malaria vaccine approved as hopes raised for new, better ones
Mosquirix prevents just 30% of severe malaria cases in young children prompting a guarded welcome
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Article
AstraZeneca explores new frontiers through academic collaborations
The important of partnerships between industry and academia to drive innovation