All Drug discovery and development articles – Page 3
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OpinionA spanner in the works
Most drugs work by breaking or stopping something, rather than by making something faster or better
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Business
Moderna sued over Covid-19 vaccine-related patents
Arbutus and Genevant say lipid nanoparticles that protect mRNA infringe six key patents
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Business
Trials start of mRNA vaccine for HIV
First steps towards protection from the many and variable viral strains
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Opinion
The shadow of drug resistance
Why do some medicines stop working, and can we avoid it for Covid-19 antivirals?
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Opinion
The law of conservation of data
AI and machine learning are useful and powerful, but they need high quality data inputs that aren’t available yet for drug discovery
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Opinion
When regulatory cooperation goes too far, we all lose
Were FDA staff unduly influenced by Biogen in approving Alzheimer’s antibody?
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Business
Pharmaceuticals roundup 2021
It’s been another dramatic, pandemic-dominated year for the pharmaceutical industry
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Webinar
Using flow chemistry to give early drug discovery processes a boost
Discover how pioneering modular flow chemistry technologies can unlock the potential for discovery chemists to accelerate research
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Business
Pfizer sues former employee for alleged trade secret theft
Chun Xiao Li downloaded thousands of confidential documents before resigning
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Business
Covid-19 antivirals surge forward
Promising results from Pfizer trial, while UK approves Merck & Co’s molnupiravir
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Research
Gallium helps sneak antibiotic payload into bacterial cells
Compound is more potent than parent drug ciprofloxacin against Staphylococcus aureus
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Feature
mRNA vaccines for Covid and beyond
Already hailed as a miracle, the new vaccine technology could protect us from other diseases, Clare Sansom finds
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Sponsored
Facilitating the future
A view from the top at Johnson Matthey on the future of drug development
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Sponsored
AstraZeneca explores new frontiers through academic collaborations
The important of partnerships between industry and academia to drive innovation
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Business
New antiviral impresses against Covid-19
Merck & Co and Ridgeback’s molnupiravir reduces risk of hospitalisation and death, and may work against other coronaviruses
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Opinion
Where are the Covid-19 drugs?
Small molecules appear to be lagging behind development of vaccine and antibody treatments
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Research
Programmable peptoid template for disrupting protein–protein interactions inside cells
System optimises residues involved in binding target independently from those that promote membrane permeability
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Research
Method to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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Business
Fully synthetic proteins make tailored medicines
Bright Peak Therapeutics makes modified protein drugs from scratch
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News
Explainer: The science of alkyl nitrites aka poppers
From their origins as 19th century angina treatment to becoming an important part of gay subculture, these recreational drugs exist in a legal limbo
