Drug discovery and development – Page 4
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ResearchMapping metabolite disturbances by drugs
High-throughput metabolomic profiling gives insight into unpredictable drug effects
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ResearchHow AI is transforming chemistry research
Artificial intelligence is revolutionising everything from workflows to networking - so how can you bring AI into your research practice?
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BusinessJ&J’s Intra-Cellular deal could signal more mega-mergers for 2025
£15 billion deal for neuroscience biotech aims to replace revenues from patent expiries
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OpinionSharing the burden of contraception could also mean sharing the risk
What if risk assessments for contraception considered the sum of risk to both members of a couple?
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FeatureOn the trail of the male contraceptive pill
As multiple novel male contraception compounds enter clinical trials, is family planning about to undergo a second revolution? James Mitchell Crow reports
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OpinionRobots queuing up to fail
Claims of an AI revolution in drug discovery are missing the biggest problem
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FeatureThe promise of drugs that send proteins to the shredder
Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to strategic discovery
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ResearchFirst potential antidote for hydrogen sulfide poisoning created
A novel molecule can work as a multi-gas antidote providing potential treatment for carbon monoxide, cyanide and hydrogen sulfide poisoning
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ResearchAfter-school club students in Chicago discover promising bioactive compound via goose droppings
Chicago antibiotic discovery lab engages middle school students from underrepresented communities in hands-on research
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WebinarHarnessing hormones for health: Taking GLP-1 from research to reality
Learn about the groundbreaking science research behind the GLP-1 revolution
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BusinessPharmaceuticals roundup 2024
Diabetes and weight loss drugs have surged in popularity, revealing supply frailties
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ResearchmRNA therapy might one day treat deadly pre-eclampsia in pregnant women
Therapy helped pregnant mice to regrow placental blood vessels
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ResearchAI tool learns to build molecules fragment by fragment
Software tasked with designing a type-II kinase inhibitor suggests 97 candidates in 10 minutes, three of which were both synthesisable and effective at micromolar and nanomolar concentrations
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BusinessEurope reconsiders Alzheimer’s antibody approval
Leqembi recommended for approval with restrictions to reduce side effect risk
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BusinessUS approves schizophrenia drug with new mode of action
Cobenfy promises to better address negative symptoms than existing antipsychotics
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WebinarEmerging routes to new therapeutics: Highlights from winning Horizon Prize teams
Discover how new therapeutics have the potential to address unmet medical needs
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BusinessUS industry braced for change as election looms
Regulation, trade tariffs and innovation support top lists of concerns
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OpinionBeing wrong is almost inevitable
On the tightrope of expressing your opinion, you always risk looking a fool
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OpinionGLP-1 drugs could be more than a win–win for weight loss
Semaglutide and tirzepatide are changing lives, and could change our attitudes