Drug discovery and development – Page 4
-
Business
New Covid-19 antiviral cuts symptoms by 1.5 days
Simnotrelvir already has emergency approval in China
-
-
News
Explainer: A new antibiotic class has been discovered – how excited should we get?
With 10 million people a year forecast to die a year as a result of antimicrobial resistance by 2050 many new antibiotics are urgently needed
-
Research
Machine learning identifies promising antibacterial ruthenium-based drug candidates
Algorithm demonstrated a success rate six times higher than a random screening against resistant bacteria
-
Opinion
Exploring new fragments of chemical space
How medicinal and process chemists are working together to build better drugs
-
Business
Pharmaceuticals roundup 2023
Regulatory and pricing reforms have topped industry agendas in 2023, while weight loss drugs surged and Covid-19 therapies waned
-
Feature
Cubanes help drugs take the strain
Medicinal chemists are increasingly exploring strained ring systems, George Barsted reports, believing they can serve as replacements for conventional building blocks in pharmaceuticals
-
Research
Antibiotic adjuvant designed to subvert bacterial defence mechanisms
Amphiphilic molecule helps obsolete antibiotics accumulate and act within bacteria
-
Business
Weight-loss drug shortages prompt copycats and counterfeits
Novo Nordisk and Eli Lilly have struggled to meet huge demand for new hormone mimic obesity treatments
-
Research
Underwater device reveals marine chemical diversity
I-Smel device probes metabolites produced by Mediterranean sponges
-
Feature
Battling long Covid with drugs
The challenge of finding drugs for a poorly understood disease with many symptoms is clear. Clare Sansom looks at the work going on to help the people suffering in its shadow
-
Opinion
Letters: October 2023
Readers discuss antibiotic challenges, muse about micrographs and remember Philip Eaton
-
News
mRNA vaccine pioneers win medicine Nobel prize
Katalin Karikó and Drew Weissman honoured for breakthroughs that enable the rapid development of new vaccines, including several of those used against Covid-19
-
Feature
The drug developers fighting the antibiotic resistance problem
Andy Extance talks to the researchers innovating across different drug classes in the hunt to develop new treatments
-
-
-
Business
How can we maintain the effectiveness of existing antimicrobials?
Reducing environmental pollution and tackling quality issues to stave off resistance
-
Careers
Sharing antimicrobial expertise with Parliament
Emily Stevenson is one of two interns working alongside Green Party peer, Baroness Natalie Bennett
-
Feature
Who will pay for new antibiotics?
Governments around the world are starting to consider alternative funding models and incentives for antibiotics. Katrina Megget asks if it is enough
-
Opinion
Surviving in the war of all against all
Cancers and bacteria develop resistance to drugs in remarkably similar ways