All Drug discovery and development articles – Page 4
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WebinarAutomated capsule chemistry with Synple: do more, faster
Synple’s automated synthesis technology allows discovery chemists to accelerate research and improve efficiency
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Business
The multi-pronged search for Covid-19 treatments
Drugs that block infection or reduce inflammation will complement vaccine protection
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Business
Budget cuts at UK medicines regulator raise eyebrows
MHRA to cut 300 jobs amid financial pressures arising from Brexit
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Business
Brewing up plant-inspired medicines
Antheia reconstructs complex biochemical pathways in yeasts to speed up production of natural product-based drugs
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Business
Developing countries sidelined in Covid-19 vaccine scramble
Lack of funds and local manufacturing capacity has prevented Covax from competing with wealthier nations’ self-interest
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Business
Pfizer backs protein degrader drugs with Arvinas deal
$1bn investment to commercialise breast cancer treatment
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Webinar
Harness the power of electricity to make organic compounds
Join us to learn how to use batch-type cells in preparatory electrosynthesis
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Feature
One hundred years of insulin
Mike Sutton looks at the journey the diabetes treatment took from the Toronto miracle to mass-production – via a controversial trip to Stockholm
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Opinion
Opening up a cellular black box
Working out how biomolecular condensates work may reveal a lot about the success or failure of different drugs
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News
Race to understand Sars-CoV-2 variants amid fears virus might evade vaccines
Biochemical basis behind coronavirus variants’ success could hold key to defeating them
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Business
BMS and Eisai agree antibody-drug conjugate commercialisation deal
Companies will jointly develop cancer treatment, with BMS paying up to $3 billion for shared rights
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Feature
Supermetals versus superbugs
With pathogenic bacteria rapidly overcoming our arsenal of organic antibiotics, James Mitchell Crow asks if it is time to revisit metal-based antimicrobials
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Business
Regeneron’s Covid-19 antibodies help those who can’t make their own
Regn-Cov2 reduces deaths and shortens hospitalisation for these patients, even when given at late stages of infection
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Business
Alzheimer’s antibody gets surprise US approval
Good news for industry and future drug approvals, but physicians doubt it will be effective for most patients
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Business
Morphosys agrees to buy cancer epigenetics specialist Constellation
$1.7bn deal will be funded by selling rights to royalties on existing drugs
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Business
Striving to bolster the antibiotic pipeline before it becomes the next crisis
It’s been almost 10 years since the world was warned of a post-antibiotic apocalypse. Katrina Megget takes a look at the initiatives trying to support antimicrobial R&D
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Opinion
The side effects of being unique
Even the largest clinical trials won’t capture all possible bad reactions to a drug – we need pharmacovigilance
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Research
Machine learning tool sets out to find new antimicrobial peptides
IBM researchers say their fully automated AI-driven system could speed up the discovery of molecules for novel antibiotics
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Business
Antibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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Opinion
How the pandemic might change drug research
Derek Lowe muses on some positive lessons learned
