Drug discovery and development – Page 4
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ResearchNanobodies from alpacas and llamas could hold the key to a universal antivenom
Novel nanobody mix protects against 17 African snake species
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BusinessNovartis spends on deals to offset patent losses
$12 billion Avidity acquisition is the latest pipeline-pumping transaction
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ResearchThis fragment-based drug discovery library is designed to be sociable
Study targets a key bottleneck in hit to lead optimisation by designing fragments that are both structurally diverse and easy to elaborate
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WebinarSYNTHIA for chemists: faster route design
Discover how SYNTHIA accelerates retrosynthesis by helping chemists design, compare and refine routes with customisable filters and commercial building blocks
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ResearchUltrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms
Hybrid molecule featuring leech, tsetse fly and flea peptide fragments binds thrombin at three sites
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WebinarDeveloping a CITK protein degrader using the QuicTPD™ platform
Learn about the latest technology to accelerate the design of cancer treatments
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BusinessArvinas and Pfizer seek a new home for protein degrader drug
Companies offer bifunctional cancer drug vepdegestrant to new partners after disappointing trial results
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BusinessNovo Nordisk’s new chief cuts 9000 jobs
Danish firm shifts strategy after struggling to capitalise on its weight loss drugs
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OpinionIs UK pharma really ‘uninvestable’?
Merck & Co, AstraZeneca (AZ) and Eli Lilly pulling UK projects highlights the precarious position of the country’s life sciences industry
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BusinessUK loses life sciences investment as pharma companies halt expansion plans
Industry seeks greater share of healthcare spending to support innovation
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WebinarIon suppression correction and normalisation in metabolomics
Join us to learn new ways to improve data consistency with mass spectrometry
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OpinionLiver toxicity remains an unpredictable hurdle for medicinal chemists
The liver’s complex role in metabolising drugs makes it both a critical consideration and potential stumbling block
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WebinarLipidomics for antibiotic resistance (AMR) mechanisms
Discover how microbial antibiotic exposure triggers lipidomic changes, offering insight into how lipids contribute to resistance mechanisms
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ResearchNew class of antifungals show potent effects against priority pathogens
Coniotins, found in another fungus, is effective against drug-resistant pathogenic fungi
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WebinarLost in space, found in data: real-world scientific exploration and discovery
Join us as we navigate the world of multidimensional spaces in data discovery methodology
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ResearchAntibiotics designed with the help of AI attack bacteria in entirely new ways
Two new compounds display potent activity against deadly drug-resistant bacteria
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BusinessWill oral weight loss drugs challenge injectables?
Pills may offer convenience for manufacturers, but it’s not clear they will overtake existing drugs
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BusinessThe challenge of developing oral alternatives to peptide weight loss drugs
Companies are racing to develop alternatives to injectable diabetes and weight loss drugs
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NewsUS government cancels mRNA vaccine research
Experts fear industrial and academic research may move abroad after infectious disease projects cancelled
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BusinessMerck & Co to cut 6000 jobs, Moderna to cut around 500
Both firms aiming to make significant reductions in annual costs by reorganising