All Drug discovery and development articles – Page 9
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ResearchTargeted nanoparticles swell-up to kill cancer cells
Nanoparticles covered with charged ligands can kill errant cancer cells but leave normal cells unharmed
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Podcast
Minoxidil and Finasteride
Catherine Hodges explores the chemical solutions to thinning hair and patchy beards, examining the popularity of minoxidil and the cautionary tale of finasteride
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Business
RNA vaccines are coronavirus frontrunners
Several groups have potential Sars-CoV-2 vaccines ready or close to testing, thanks to rapid development pathways
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Research
Metal complexes outperform organics in antimicrobial analysis on crowdsourced compounds
Could this study prompt drug developers to rethink their reluctance to making metal-based pharmaceuticals?
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Research
AI tool screens 107 million molecules, discovers potent new antibiotics
Deep learning approach could help in fight against drug-resistant bacteria
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Opinion
Two heads are better than one
Bifunctionals show that sometimes simply tethering two useful molecules together unlocks some useful activity
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Feature
Adjuvants: vaccines’ hidden helpers
Anthony King examines a crucial part of vaccines that can significantly boost their performance, but which often go unrecognised
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Business
The race to fight coronavirus
While genome sequences enable testing and vaccine efforts, companies are donating existing antiviral drugs to explore repurposing
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Sponsored
Transforming innovation for startups
Green polymer specialists Novomer and biotech startup SynbiCite optimised industrial and biotech processes using design of experiment software from JMP
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Feature
The search for cancer vaccines
Claire Jarvis looks at ongoing work to prevent the disease – and convince a sceptical community of their seriousness
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Business
Cancer and rare diseases dominated 2019 drug approvals
More streamlined review processes and changing R&D priorities have contributed to sustained increase in new medicines
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Opinion
Startup EQRx claims it can revolutionise drug discovery
If it can deliver reasonable drugs at knock-down prices, will providers be convinced?
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Research
Sugars designed to disrupt bacterial cell wall biosynthesis
Rare monosaccharides explore concept for new narrow-spectrum antibiotics
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Webinar
Renewable resources: the future role of lignins
Learn how to gain more detailed insight into your lignin samples with Antje Potthast from Waters
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Research
Synthetic strategy exploits fluxional nitrogen to deliver three chiral centres for the price of one
Innovative method amplifies chirality and complexity in medicinally relevant cyclic hydrazines
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Business
Revived Alzheimer’s antibody met with guarded optimism
Biogen’s aducanumab offers the possibility to slow disease progress, but regulators will likely want more convincing evidence
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Research
Inorganic fragment library ready to help drug discoverers reach neglected regions of chemical space
A new approach to fragment-based drug design
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Business
Pharmaceuticals roundup 2019
Under the shadow of political turmoil and major lawsuits, the industry returned to its strengths – making new drugs, and finding new ways to do it better
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Podcast
Oxycodone and hydrocodone
Frances Addison examines how our quest to control and manage pain has led to a modern medical crisis, as opioids oxycodone and hydrocodone are among the most abused prescription medications in the US
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News
European commission gives green light to first Ebola vaccine
Drug shown to be effective and safe following clinical trials involving 16,000 people
