Drug discovery and development – Page 2
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ResearchFirst potential antidote for hydrogen sulfide poisoning created
A novel molecule can work as a multi-gas antidote providing potential treatment for carbon monoxide, cyanide and hydrogen sulfide poisoning
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ResearchAfter-school club students in Chicago discover promising bioactive compound via goose droppings
Chicago antibiotic discovery lab engages middle school students from underrepresented communities in hands-on research
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WebinarHarnessing hormones for health: Taking GLP-1 from research to reality
Learn about the groundbreaking science research behind the GLP-1 revolution
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BusinessPharmaceuticals roundup 2024
Diabetes and weight loss drugs have surged in popularity, revealing supply frailties
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ResearchmRNA therapy might one day treat deadly pre-eclampsia in pregnant women
Therapy helped pregnant mice to regrow placental blood vessels
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ResearchAI tool learns to build molecules fragment by fragment
Software tasked with designing a type-II kinase inhibitor suggests 97 candidates in 10 minutes, three of which were both synthesisable and effective at micromolar and nanomolar concentrations
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BusinessEurope reconsiders Alzheimer’s antibody approval
Leqembi recommended for approval with restrictions to reduce side effect risk
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BusinessUS approves schizophrenia drug with new mode of action
Cobenfy promises to better address negative symptoms than existing antipsychotics
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WebinarEmerging routes to new therapeutics: Highlights from winning Horizon Prize teams
Discover how new therapeutics have the potential to address unmet medical needs
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BusinessUS industry braced for change as election looms
Regulation, trade tariffs and innovation support top lists of concerns
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OpinionBeing wrong is almost inevitable
On the tightrope of expressing your opinion, you always risk looking a fool
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OpinionGLP-1 drugs could be more than a win–win for weight loss
Semaglutide and tirzepatide are changing lives, and could change our attitudes
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FeatureThe GLP-1 weight loss revolution
Glucagon-like peptide-1 agonist drugs, such as semaglutide, could save countless lives at risk due to diabetes and obesity. Rachel Brazil looks at the difficulties in making the peptides themselves, and what’s coming next
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ResearchPotential new class of antibiotics takes on flesh-eating infections
Peptide-mimicking compounds target bacterial cell walls
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ResearchInnovative antibacterial strategy shows promise for treating infections
New antibiotic mechanism sees molecule infiltrate bacterial cells and destroy them from the inside
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WebinarAI meets chemistry: Standigm’s breakthrough with Synthia Retrosynthesis Software
Discover how Standigm’s use of Synthia can accelerate AI-driven drug discovery
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OpinionMedicinal chemistry’s biological blind spots
Despite advances in modern medicine, there are some big gaps in our knowledge
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ResearchCompanion compound for naloxone could boost opioid reversal effects, save lives
Discovery could help in fight against super-strength opioids such as fentanyl
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FeatureBypassing the blood–brain barrier
Researchers are on a quest to outsmart and overcome the sophisticated security system of the brain. Julia Robinson reports on some of the approaches being studied