Drug discovery and development – Page 2
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BusinessNovartis spends on deals to offset patent losses
$12 billion Avidity acquisition is the latest pipeline-pumping transaction
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ResearchThis fragment-based drug discovery library is designed to be sociable
Study targets a key bottleneck in hit to lead optimisation by designing fragments that are both structurally diverse and easy to elaborate
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WebinarSYNTHIA for chemists: faster route design
Discover how SYNTHIA accelerates retrosynthesis by helping chemists design, compare and refine routes with customisable filters and commercial building blocks
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ResearchUltrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms
Hybrid molecule featuring leech, tsetse fly and flea peptide fragments binds thrombin at three sites
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WebinarDeveloping a CITK protein degrader using the QuicTPD™ platform
Learn about the latest technology to accelerate the design of cancer treatments
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BusinessArvinas and Pfizer seek a new home for protein degrader drug
Companies offer bifunctional cancer drug vepdegestrant to new partners after disappointing trial results
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BusinessNovo Nordisk’s new chief cuts 9000 jobs
Danish firm shifts strategy after struggling to capitalise on its weight loss drugs
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OpinionIs UK pharma really ‘uninvestable’?
Merck & Co, AstraZeneca (AZ) and Eli Lilly pulling UK projects highlights the precarious position of the country’s life sciences industry
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BusinessUK loses life sciences investment as pharma companies halt expansion plans
Industry seeks greater share of healthcare spending to support innovation
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WebinarIon suppression correction and normalisation in metabolomics
Join us to learn new ways to improve data consistency with mass spectrometry
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OpinionLiver toxicity remains an unpredictable hurdle for medicinal chemists
The liver’s complex role in metabolising drugs makes it both a critical consideration and potential stumbling block
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WebinarLipidomics for antibiotic resistance (AMR) mechanisms
Discover how microbial antibiotic exposure triggers lipidomic changes, offering insight into how lipids contribute to resistance mechanisms
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ResearchNew class of antifungals show potent effects against priority pathogens
Coniotins, found in another fungus, is effective against drug-resistant pathogenic fungi
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WebinarLost in space, found in data: real-world scientific exploration and discovery
Join us as we navigate the world of multidimensional spaces in data discovery methodology
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ResearchAntibiotics designed with the help of AI attack bacteria in entirely new ways
Two new compounds display potent activity against deadly drug-resistant bacteria
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BusinessWill oral weight loss drugs challenge injectables?
Pills may offer convenience for manufacturers, but it’s not clear they will overtake existing drugs
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BusinessThe challenge of developing oral alternatives to peptide weight loss drugs
Companies are racing to develop alternatives to injectable diabetes and weight loss drugs
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NewsUS government cancels mRNA vaccine research
Experts fear industrial and academic research may move abroad after infectious disease projects cancelled
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BusinessMerck & Co to cut 6000 jobs, Moderna to cut around 500
Both firms aiming to make significant reductions in annual costs by reorganising
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ResearchAI tools turned to creating designer proteins for personalised cancer therapies and antibiotics
Powerful new class of AI model could dramatically speed up process of producing new kinds of drug candidates